Reactome | FCN2 [extracellular region]

FCN2 [extracellular region]

Stable Identifier

R-GGA-2530451

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

extracellular region

Synonyms

FCN1, A0A1D5P1R2

Locations in the PathwayBrowser

Expand all

Immune System (Gallus gallus)

- Innate Immune System (Gallus gallus)
  - Complement cascade (Gallus gallus)
    - Initial triggering of complement (Gallus gallus)
      - Conversion of C2 into C2a and C2b (Gallus gallus)
        
        C4 activators [plasma membrane] (Gallus gallus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Gallus gallus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
      - Conversion of C4 into C4a and C4b (Gallus gallus)
        
        C4 activators [plasma membrane] (Gallus gallus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Gallus gallus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
      - Creation of C4 and C2 activators (Gallus gallus)
        
        Lectin pathway of complement activation (Gallus gallus)
        
        Activation of MASPs (Gallus gallus)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Gallus gallus)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Gallus gallus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Gallus gallus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
        
        Ficolins bind to repetitive carbohydrate structures on the target cell surface (Gallus gallus)
        
        Ficolin-1 binds to molecular patterns on the target cell surface (Gallus gallus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Gallus gallus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Gallus gallus)
        
        FCN1 dodecamer [extracellular region] (Gallus gallus)
        
        FCN1 trimer [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
  - Neutrophil degranulation (Gallus gallus)
    - Exocytosis of ficolin-rich granule lumen proteins (Gallus gallus)
      - Ficolin-rich granule lumen proteins [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)
    - Exocytosis of secretory granule lumen proteins (Gallus gallus)
      - Secretory granule lumen proteins [extracellular region] (Gallus gallus)
        
        FCN2 [extracellular region] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5P1R2

Gene Names

FCN2

Reference Genes

BioGPS Gene:417298 FCN2

ENSEMBL:ENSGALG00000040771

KEGG Gene (Gallus gallus):417298 FCN2

Monarch:417298 FCN2

NCBI Gene:417298 FCN2

Reference Transcript

RefSeq:XM_004945743.2 FCN2

Other Identifiers

417298

GT_A_87_P012535

GT_Sp_Chicken_CN233949_5741

Gga.12312.1.S1_a_at

Participates

as a member of

as a component of

FCN1 trimer [extracellular region] (Gallus gallus)

Other forms of this molecule

FCN2 [secretory granule lumen]

FCN2 [ficolin-1-rich granule lumen]

FCN2 [extracellular region]

Inferred From

FCN1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_004945800.1

OpenTargets

ENSG00000160339

Ensembl

ENSGALT00000054785, ENSGALP00000046601, ENSGALG00000040771