CREM (CREMP) binds to surface-bound C3b or C4b

Stable Identifier
R-GGA-2530584
Type
Reaction [binding]
Species
Gallus gallus
Compartment
plasma membrane
ReviewStatus
5/5
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CREM (CREMP) binds to surface-bound C3b or C4b
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CREM, a complement regulatory protein in chicken, consists of 5 short consensus repeats (SCRs).This is a non-mammalian membrane-anchored C regulatory protein similar to MCP and DAF. CREM protected host cells from chicken complement-mediated cytolysis (Oshiumi H et al. 2005).
Literature References
PubMed ID Title Journal Year
16034113 Regulator of complement activation (RCA) locus in chicken: identification of chicken RCA gene cluster and functional RCA proteins

Hattori, T, Tamaki, Y, Yamada, N, Oshiumi, H, Mizuno, S, Goitsuka, R, Seya, T, Matsumoto, M, Ohba, S, Katoh, J, Shida, K, Kimura, Y, Inoue, N

J. Immunol. 2005
11123320 A novel chicken membrane-associated complement regulatory protein: molecular cloning and functional characterization

Fukui, A, Seya, T, Nishizawa, Y, Inoue, N, Matsumoto, M, Toyoshima, K, Nomura, M

J. Immunol. 2001
Participants
Input
Output
Participates
as an event of
Authored
Shamovsky, V  (2012-12-20)
Reviewed
D'Eustachio, P  (2012-11-07)
Jupe, S  (2013-01-31)
Created
Shamovsky, V  (2012-10-17)
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