Hydrolysis of C4b

Stable Identifier
R-GGA-2859050
Type
Reaction [transition]
Species
Gallus gallus
Compartment
extracellular region
ReviewStatus
5/5
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Hydrolysis of C4b
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
C4b binding to the target surface is regulated by a hydrolysis reaction that irreversibly inactivates C4b. This event is inferred from the annotated human reaction.
Literature References
PubMed ID Title Journal Year
8495193 Covalent binding properties of the human complement protein C4 and hydrolysis rate of the internal thioester upon activation

Campbell, RD, Sepp, A, Law, SK, Anderson, MJ, Willis, AC, Dodds, AW

Protein Sci 1993
Participants
Input
Output
Participates
as an event of
Inferred From
Hydrolysis of internal thioester in C4b (Homo sapiens)
Authored
Shamovsky, V  (2012-12-20)
Reviewed
D'Eustachio, P  (2012-11-07)
Jupe, S  (2013-01-31)
Created
Shamovsky, V  (2012-12-19)
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