Reactome | GATAD2A [nucleoplasm]

GATAD2A [nucleoplasm]

Stable Identifier

R-GGA-3702077

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

GATAD2A, A0A1D5PFQ6

Locations in the PathwayBrowser

Expand all

Chromatin organization (Gallus gallus)

- Chromatin modifying enzymes (Gallus gallus)
  - HDACs deacetylate histones (Gallus gallus)
    - HDAC1:2-containing complex binds HDAC2 Inhibitors (Gallus gallus)
      - HDAC1:2-containing complex [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)
      - HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Gallus gallus)
        
        HDAC1:2-containing complex [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)
    - HDAC1:2-containing complex deacetylate histones (Gallus gallus)
      - HDAC1:2-containing complex [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)
      - HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Gallus gallus)
        
        HDAC1:2-containing complex [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)

Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase I Transcription (Gallus gallus)
  - RNA Polymerase I Promoter Clearance (Gallus gallus)
    - RNA Polymerase I Transcription Initiation (Gallus gallus)
      - Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Gallus gallus)
        
        TTF-I:Sal Box:CSB:G9a:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)

Signal Transduction (Gallus gallus)

- Intracellular signaling by second messengers (Gallus gallus)
  - PIP3 activates AKT signaling (Gallus gallus)
    - PTEN Regulation (Gallus gallus)
      - Regulation of PTEN gene transcription (Gallus gallus)
        
        SALL4 recruits NuRD to PTEN gene (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)
        
        SALL4:NuRD:PTEN gene [nucleoplasm] (Gallus gallus)
        
        SALL4:NuRD [nucleoplasm] (Gallus gallus)
        
        NuRD complex [nucleoplasm] (Gallus gallus)
        
        (GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)
        
        GATAD2A [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5PFQ6

Gene Names

GATAD2A

Reference Genes

BioGPS Gene:420109 GATAD2A

ENSEMBL:ENSGALG00000042900

ENSEMBL:ENSGALG00010028516.1 GATAD2A

Monarch:420109 GATAD2A

NCBI Gene:420109 GATAD2A

Reference Transcript

Other Identifiers

420109

GO:0000122

GO:0003677

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0016581

GO:0030674

GO:0043226

GO:0043565

GO:0045892

GO:0060090

GT_A_87_P055811

GT_A_87_P125763

Gga.8784.1.S1_at

Gga.8784.2.S1_a_at

Participates

as a candidate of

(GATAD2A, GATAD2B) [nucleoplasm] (Gallus gallus)

Inferred From

GATAD2A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_015155529.1, XP_015155531.1, XP_015155528.1, XP_015155530.1

OpenTargets

ENSG00000167491

Ensembl

ENSGALG00010028516, ENSGALP00010042507, ENSGALT00010069065