malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]

Stable Identifier
R-GGA-372852
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol, mitochondrial inner membrane, mitochondrial matrix
ReviewStatus
5/5
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malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
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SLC25A10, the mitochondrial dicarboxylate carrier protein in the inner mitochondrial membrane, mediates the reversible exchange of mitochondrial malate for cytosolic phosphate. No chicken transport protein capable of mediating this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human SLC25A10 has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.
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Catalyst Activity

dicarboxylic acid transmembrane transporter activity of SLC25A10 [mitochondrial inner membrane]

Physical Entity
SLC25A10 [mitochondrial inner membrane] (Gallus gallus)
Activity
dicarboxylic acid transmembrane transporter activity (GO:0005310)
Inferred From
SLC25A10 mediates exchange of malate and phosphate (Homo sapiens)
Authored
D'Eustachio, P  (2008-09-10)
Reviewed
Harris, RA  (2008-09-10)
Created
D'Eustachio, P  (2008-07-08)
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