Reactome | SST [extracellular region]

SST [extracellular region]

Stable Identifier

R-GGA-374738

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

extracellular region

Synonyms

SST(103-116), P33094

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Peptide ligand-binding receptors (Gallus gallus)
        
        Somatostatin receptors bind somatostatin and cortistatin (Gallus gallus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)
        
        Somatostatin, cortistatin [extracellular region] (Gallus gallus)
        
        SST [extracellular region] (Gallus gallus)

External Reference Information

External Reference

UniProt:P33094

Gene Names

SST

Reference Genes

BioGPS Gene:396279 SST

ENSEMBL:ENSGALG00000007361

KEGG Gene (Gallus gallus):396279 SST

Monarch:396279 SST

NCBI Gene:396279 SST

Reference Transcript

RefSeq:NM_205336.1 SST

Participates

as a member of

Somatostatin, cortistatin [extracellular region] (Gallus gallus)

Other forms of this molecule

SST [extracellular region]

Inferred From

Somatostatin [extracellular region] (Homo sapiens)

SST(103-116) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_990667.1

OpenTargets

ENSG00000157005

PRO

P33094