Reactome | NMBR [plasma membrane]

NMBR [plasma membrane]

Stable Identifier

R-GGA-375357

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

NMBR, E1BRP1

Locations in the PathwayBrowser

Expand all

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (q) signalling events (Gallus gallus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Peptide ligand-binding receptors (Gallus gallus)
        
        Bombesin-like receptors bind bombesin homologues (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Gallus gallus)
        
        Bombesin-like receptor [plasma membrane] (Gallus gallus)
        
        NMBR [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BRP1

Gene Names

NMBR

Reference Genes

BioGPS Gene:428610 NMBR

ENSEMBL:ENSGALG00000013813

ENSEMBL:ENSGALG00010005824.1 NMBR

KEGG Gene (Gallus gallus):428610 NMBR

Monarch:428610 NMBR

NCBI Gene:428610 NMBR

Reference Transcript

RefSeq:XM_426167.4 NMBR

Other Identifiers

428610

GO:0002376

GO:0004930

GO:0004946

GO:0005829

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008188

GO:0008528

GO:0016020

GO:0023052

GO:0031989

GO:0032715

GO:0032727

GO:0060089

GO:0090290

GO:0098542

GO:0140374

GO:0160023

GO:1903942

GgaAffx.8784.1.S1_at

Participates

as a member of

Bombesin-like receptor [plasma membrane] (Gallus gallus)

Inferred From

NMBR [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_426167.1

OpenTargets

ENSG00000135577

Ensembl

ENSGALT00010013868, ENSGALP00010008185, ENSGALG00010005824