Reactome | HTR2A [plasma membrane]

HTR2A [plasma membrane]

Stable Identifier

R-GGA-390947

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

HTR2A, E1BVI5

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (q) signalling events (Gallus gallus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Amine ligand-binding receptors (Gallus gallus)
        
        Serotonin receptors (Gallus gallus)
        
        5-HT2 receptor can bind serotonin (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)
        
        HTR2A-C:5HT [plasma membrane] (Gallus gallus)
        
        HTR2A-C [plasma membrane] (Gallus gallus)
        
        HTR2A [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BVI5

Gene Names

HTR2A

Reference Genes

BioGPS Gene:428070 HTR2A

ENSEMBL:ENSGALG00000016992

KEGG Gene (Gallus gallus):428070 HTR2A

Monarch:428070 HTR2A

NCBI Gene:428070 HTR2A

Reference Transcript

RefSeq:NM_001318420.1 HTR2A

Participates

as a member of

HTR2A-C [plasma membrane] (Gallus gallus)

Inferred From

HTR2A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001305349.1

OpenTargets

ENSG00000102468

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