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ROCK2 [cytosol]
Stable Identifier
R-GGA-419058
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
ROCK2, A0A3Q2TTH6
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPHB-mediated forward signaling (Gallus gallus)
RHOA:GTP binds ROCK, activating it (Gallus gallus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
Semaphorin interactions (Gallus gallus)
Sema4D in semaphorin signaling (Gallus gallus)
Sema4D induced cell migration and growth-cone collapse (Gallus gallus)
ROCK activation by RHO (Gallus gallus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,2 bind ROCKi (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (12/13) signalling events (Gallus gallus)
ROCK activation by RHO (Gallus gallus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,2 bind ROCKi (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Gallus gallus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 are activated (Gallus gallus)
RHOA:GTP:Mg2+:Activated ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate ROCKs (Gallus gallus)
ROCK activation by RHO (Gallus gallus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,2 bind ROCKi (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
ROCK1,ROCK2:ROCKi [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RHOA GTPase cycle (Gallus gallus)
RHOA binds effectors at the plasma membrane (Gallus gallus)
RHOA plasma membrane effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Gallus gallus)
RHOA plasma membrane effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOB GTPase cycle (Gallus gallus)
RHOB binds effectors at the plasma membrane (Gallus gallus)
RHOB effectors (plasma membrane) [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Gallus gallus)
RHOB effectors (plasma membrane) [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOBTB GTPase Cycle (Gallus gallus)
RHOBTB1 GTPase cycle (Gallus gallus)
RHOBTB1 binds interacting proteins at the endosome membrane (Gallus gallus)
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Gallus gallus)
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOC GTPase cycle (Gallus gallus)
RHOC binds effectors at the plasma membrane (Gallus gallus)
RHOC effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOC:GTP:RHOC effectors [plasma membrane] (Gallus gallus)
RHOC effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOH GTPase cycle (Gallus gallus)
RHOH binds effectors at the plasma membrane (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
RHOH:GTP:RHOH effectors [plasma membrane] (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
ROCK2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A3Q2TTH6
Gene Names
ROCK2
Reference Genes
BioGPS Gene:374182 ROCK2
ENSEMBL:ENSGALG00000016451
KEGG Gene (Gallus gallus):374182 ROCK2
Monarch:374182 ROCK2
NCBI Gene:374182 ROCK2
Reference Transcript
RefSeq:XM_015276085.1 ROCK2
Other Identifiers
374182
GO:0001934
GO:0003674
GO:0004672
GO:0004674
GO:0005524
GO:0005575
GO:0005622
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006464
GO:0006468
GO:0006939
GO:0007010
GO:0007049
GO:0007165
GO:0007249
GO:0007266
GO:0008150
GO:0009058
GO:0010595
GO:0010628
GO:0010825
GO:0016301
GO:0016525
GO:0018105
GO:0018107
GO:0019899
GO:0022607
GO:0030154
GO:0030335
GO:0030866
GO:0031267
GO:0032956
GO:0034330
GO:0034641
GO:0035509
GO:0035556
GO:0036464
GO:0039694
GO:0040011
GO:0043167
GO:0043226
GO:0045019
GO:0045616
GO:0048646
GO:0048856
GO:0048870
GO:0051298
GO:0051496
GO:0071394
GO:0072518
GO:0072659
GO:0150033
GO:1902004
GO:1902961
GO:1902966
GO:1902993
GO:1903140
GO:1903347
GT_A_87_P015011
GT_A_87_P125478
Gga.17943.1.S1_at
Gga.3500.1.S1_at
GgaAffx.10528.1.S1_at
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Gallus gallus)
RHOC effectors [cytosol] (Gallus gallus)
RHOBTB1 interacting proteins [cytosol] (Gallus gallus)
RHOB effectors (plasma membrane) [cytosol] (Gallus gallus)
ROCK1,ROCK2 [cytosol] (Gallus gallus)
as a candidate of
RHOH effectors [cytosol] (Gallus gallus)
Inferred From
Activated ROCK2 [cytosol]
(Homo sapiens)
ROCK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015131571.1
OpenTargets
ENSG00000134318
Ensembl
ENSGALG00000016451
,
ENSGALP00000065471
,
ENSGALT00000098757
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