Reactome | De novo synthesis of GMP

De novo synthesis of GMP

Stable Identifier

R-GGA-421223

Type

Pathway

Species

Gallus gallus

Compartment

cytosol

ReviewStatus

5/5

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GMP (guanosine monophosphate) is synthesized in two steps from IMP (inosine monophosphate). This process has not been studied in chickens but is inferred from well-studied human systems.

Participants

Events

inosine 5'-monophosphate (IMP) + NAD+ + H2O => xanthosine 5'-monophosphate (XMP) + NADH + H+ (Gallus gallus)
xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate (Gallus gallus)

Participates

as an event of

Purine metabolism (Gallus gallus)

Event Information

Go Biological Process

GMP biosynthetic process (0006177)

Authored

D'Eustachio, P (2009-05-16)

Reviewed

D'Eustachio, P (2009-05-16)

Created

D'Eustachio, P (2009-05-16)

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