uroporphyrinogen I => coproporphyrinogen I + 4 CO2

Stable Identifier
R-GGA-421459
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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uroporphyrinogen I => coproporphyrinogen I + 4 CO2
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Cytosolic UROD (uroporphyrinogen decarboxylase) catalyzes the reaction of uroporphyrinogen I to form coproporphyrinogen I and four molecules of CO2. Chicken UROD is known only as the inferred product of a gene discovered by analysis of the chicken genomic DNA sequence. Its dimerization to form an active enzyme and its catalytic activity are inferred from the properties of its better-studied human counterpart.
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Catalyst Activity

uroporphyrinogen decarboxylase activity of UROD dimer [cytosol]

Physical Entity
UROD dimer [cytosol] (Gallus gallus)
Activity
uroporphyrinogen decarboxylase activity (GO:0004853)
Inferred From
UROD decarboxylates URO1 to COPRO1 (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-19)
Created
D'Eustachio, P  (2009-05-19)
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