Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ERK2(MAPK1) [cytosol]
Stable Identifier
R-GGA-433942
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Innate Immune System (Gallus gallus)
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR15 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR2 subfamily cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR21 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR3 cascade (Gallus gallus)
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR4 cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR5 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
TLR7 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
MAPK activation in TLR cascade (Gallus gallus)
ERK activation (Gallus gallus)
activated MEK2 binds ERK2 (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
ERK2(MAPK1) [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8UWG6 MAPK1
Gene Names
MAPK1
Reference Genes
BioGPS Gene:373953 MAPK1
KEGG:gga:373953 MAPK1
Monarch:373953 MAPK1
NCBI Gene:373953 MAPK1
UCSC:Q8UWG6 MAPK1
Reference Transcript
RefSeq:XM_015275131.1 MAPK1
RefSeq:NM_204150.1 MAPK1
Other Identifiers
373953
GO:0000165
GO:0001784
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0005634
GO:0005737
GO:0005739
GO:0005813
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0006974
GO:0007507
GO:0008286
GO:0008353
GO:0009887
GO:0010759
GO:0010800
GO:0014032
GO:0014044
GO:0016301
GO:0016740
GO:0019858
GO:0019902
GO:0030154
GO:0030278
GO:0030521
GO:0030641
GO:0030878
GO:0031143
GO:0031663
GO:0032206
GO:0032496
GO:0033043
GO:0033598
GO:0034198
GO:0034614
GO:0035094
GO:0038127
GO:0038133
GO:0042473
GO:0042552
GO:0042802
GO:0043226
GO:0043330
GO:0043401
GO:0045542
GO:0045596
GO:0048009
GO:0048538
GO:0048856
GO:0050847
GO:0050852
GO:0050853
GO:0051403
GO:0055086
GO:0060020
GO:0060291
GO:0060324
GO:0060425
GO:0060440
GO:0060716
GO:0061308
GO:0070371
GO:0070849
GO:0071276
GO:0071356
GO:0120041
GO:0140096
GT_A_87_P012287
GT_A_87_P035308
GT_A_87_P138103
GT_Sp_Chicken_CN217549_1021
GT_Sp_Chicken_CN221028_2787
GT_Xhyb_Chicken_CN233245_3398
GT_Xhyb_Chicken_CO760520_4177
Gga.15707.1.S1_at
Gga.19031.1.S1_at
Gga.2163.1.S1_at
Participates
as an input of
activated MEK2 binds ERK2 (Gallus gallus)
as a component of
phospho MEK2 : ERK2 [cytosol] (Gallus gallus)
Other forms of this molecule
phospho-ERK2 [nucleoplasm]
phospho-ERK2 [cytosol]
Cross References
ENSEMBL
ENSGALP00010036279
,
ENSGALT00010059417
,
ENSGALG00010024358
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text