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About
What is Reactome ?
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Digital Preservation
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RAC1:GTP [plasma membrane]
Stable Identifier
R-GGA-442641
Type
Complex
Species
Gallus gallus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH-ephrin mediated repulsion of cells (Gallus gallus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
EPHB-mediated forward signaling (Gallus gallus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
L1CAM interactions (Gallus gallus)
Signal transduction by L1 (Gallus gallus)
Activation of Rac1 by VAV2 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Interaction of PAK1 with Rac1-GTP (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
pPAK1:Rac1-GTP [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Semaphorin interactions (Gallus gallus)
Sema3A PAK dependent Axon repulsion (Gallus gallus)
Activation of PAK by Rac1 (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Phosphorylation of LIMK-1 by PAK (Gallus gallus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Sema4D in semaphorin signaling (Gallus gallus)
Sema4D mediated inhibition of cell attachment and migration (Gallus gallus)
Active Rac1 interacts with Plexin-B1:Sema4D (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent Vav1 pathway (Gallus gallus)
Activation of PAKs by RAC1 and CDC42 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Activation of Rac1 by pVav1 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
Activation of RAC1 by VAV2/3 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Activation of RAC1 by VAV (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Recruitment of PAK to the membrane by binding active RAC1 (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Activation of RAC1 by VAV (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Autophosphorylation of PAK1 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 and CDC42 activate PAK1 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1,RAC2,RHOG activate PI3K (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK6/MAPK4 signaling (Gallus gallus)
Activation of PAKs by RAC1 and CDC42 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signaling by Non-Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PTK6 (Gallus gallus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Gallus gallus)
Activation of RAC1 by the PXN:CRK complex (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by MET (Gallus gallus)
MET promotes cell motility (Gallus gallus)
MET activates RAP1 and RAC1 (Gallus gallus)
DOCK7 activates RAC1 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signaling by NTRKs (Gallus gallus)
Signaling by NTRK2 (TRKB) (Gallus gallus)
Activated NTRK2 signals through FYN (Gallus gallus)
NTRK2 activates RAC1 (Gallus gallus)
DOCK3 activates RAC1 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
PAK1-3 autophosphorylates (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
PAK1-3 dimer disassociates (Gallus gallus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 binds PAK1-3 (Gallus gallus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate Formins (Gallus gallus)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Gallus gallus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
RAC1:GTP:FMNL1 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Gallus gallus)
RAC1:GTP:FMNL1 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RHO GTPases Activate NADPH Oxidases (Gallus gallus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
NOX1 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)
NOX3 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP binds NOX1 complex (Gallus gallus)
NOX1 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP binds NOX3 complex (Gallus gallus)
NOX3 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RHO GTPases Activate WASPs and WAVEs (Gallus gallus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RHO GTPases activate IQGAPs (Gallus gallus)
GTP-bound RAC1 and CDC42 bind IQGAPs (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
IQGAPs bind CALM1 (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
IQGAPs bind F-actin, which is inhibited by calmodulin (Gallus gallus)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Gallus gallus)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RHO GTPases activate PAKs (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 and CDC42 activate PAK1 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 and CDC42 activate PAK2 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 and CDC42 activate PAK3 (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 GAPs stimulate RAC1 GTPase activity (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 GEFs activate RAC1 (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 binds effectors at the plasma membrane (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1 translocates to the endoplasmic reticulum membrane (Gallus gallus)
RAC1:GTP [plasma membrane] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
cRac1A [plasma membrane]
(Gallus gallus)
GTP [cytosol]
Participates
as an input of
RAC1 translocates to the endoplasmic reticulum membrane (Gallus gallus)
RAC1 GAPs stimulate RAC1 GTPase activity (Gallus gallus)
RAC1 binds effectors at the plasma membrane (Gallus gallus)
Interaction of PAK1 with Rac1-GTP (Gallus gallus)
RAC1:GTP binds NOX1 complex (Gallus gallus)
RAC1:GTP binds NOX3 complex (Gallus gallus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)
Active Rac1 interacts with Plexin-B1:Sema4D (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
as an output of
RAC1 GEFs activate RAC1 (Gallus gallus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
Activation of Rac1 by VAV2 (Gallus gallus)
Activation of RAC1 by VAV2/3 (Gallus gallus)
DOCK3 activates RAC1 (Gallus gallus)
DOCK7 activates RAC1 (Gallus gallus)
Activation of RAC1 by VAV (Gallus gallus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Gallus gallus)
Activation of Rac1 by pVav1 (Gallus gallus)
Activation of RAC1 by the PXN:CRK complex (Gallus gallus)
as a component of
RAC1:GTP:RAC1 effectors [plasma membrane] (Gallus gallus)
pPAK1:Rac1-GTP [cytosol] (Gallus gallus)
NOX1 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX3 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Gallus gallus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Gallus gallus)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
RAC1:GTP:FMNL1 [plasma membrane] (Gallus gallus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Gallus gallus)
as a member of
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Gallus gallus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Gallus gallus)
Inferred From
RAC1:GTP [plasma membrane]
(Homo sapiens)
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