Reactome | TAK1 complex [cytosol]

TAK1 complex [cytosol]

Stable Identifier

R-GGA-446878

Type

Complex

Species

Gallus gallus

Compartment

cytosol

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

MAP3K7 [cytosol] (Gallus gallus)
TAB1 [cytosol] (Gallus gallus)
TAB2,TAB3 [cytosol] (Gallus gallus)

Participates

as an input of

Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Gallus gallus)
TRIKA2 binds K63polyUb-TRAF6 oligomer (Gallus gallus)
Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Gallus gallus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Gallus gallus)
ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Gallus gallus)
Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Gallus gallus)

as a component of

p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2 [plasma membrane] (Gallus gallus)
DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3 [plasma membrane] (Gallus gallus)
hp-IRAK1:K6-poly-Ub oligo-TRAF6:TAK1 complex [cytosol] (Gallus gallus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Gallus gallus)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] (Gallus gallus)

Inferred From

TAB1:TAB2,TAB3:TAK1 [cytosol] (Homo sapiens)

TAK1 complex [cytosol] (Homo sapiens)