TLR21homodimer binds to DNA

Stable Identifier
R-GGA-451506
Type
Reaction [binding]
Species
Gallus gallus
Compartment
endosome membrane, endosome
ReviewStatus
5/5
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TLR21homodimer binds to DNA
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Chicken TLR21 was shown to respond to both bacterial chromosomal DNA and synthetic CpG DNA.
Literature References
PubMed ID Title Journal Year
20498358 Chicken TLR21 is an innate CpG DNA receptor distinct from mammalian TLR9

Keestra, AM, de Zoete, MR, Bouwman, LI, van Putten, JP

J Immunol 2010
19573927 Chicken TLR21 acts as a functional homologue to mammalian TLR9 in the recognition of CpG oligodeoxynucleotides

Brownlie, R, Griebel, P, Babiuk, LA, Zhu, J, Potter, A, Mutwiri, GK, Allan, B

Mol Immunol 2009
Participants
Input
Output
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as an event of
Authored
Shamovsky, V  (2010-11-30)
Reviewed
D'Eustachio, P  (2010-12-06)
Created
Shamovsky, V  (2010-01-05)
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