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PI3K delta [cytosol]
Stable Identifier
R-GGA-508241
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
RET signaling (Gallus gallus)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Gallus gallus)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-2 family signaling (Gallus gallus)
Interleukin receptor SHC signaling (Gallus gallus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
14-3-3 zeta binding allows recruitment of PI3K (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
Interleukin receptor SHC signaling (Gallus gallus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Gallus gallus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Gallus gallus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
IL2:IL2R trimer p(Y338) beta subunit:p-SHC:GRB2:GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
Regulation of signaling by CBL (Gallus gallus)
CBL ubiquitinates PI3K (Gallus gallus)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Gallus gallus)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
PI3K delta [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
PI3K-regulatory subunits [cytosol]
(Gallus gallus)
PIK3CD [plasma membrane]
(Gallus gallus)
Participates
as a member of
p85-containing Class 1A PI3Ks [cytosol] (Gallus gallus)
Inferred From
PI3K delta [cytosol]
(Homo sapiens)
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