Reactome | STAT3 [cytosol]

STAT3 [cytosol]

Stable Identifier

R-GGA-539044

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

STAT3, Q6DV79

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q6DV79

Gene Names

STAT3

Reference Genes

BioGPS Gene:420027 STAT3

ENSEMBL:ENSGALG00000003267

KEGG Gene (Gallus gallus):420027 STAT3

Monarch:420027 STAT3

NCBI Gene:420027 STAT3

Reference Transcript

RefSeq:XM_015299598.1 STAT3
RefSeq:XM_015299599.1 STAT3
RefSeq:NM_001030931.1 STAT3

Participates

as a component of

IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2:STAT3 [plasma membrane] (Gallus gallus)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Gallus gallus)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 [plasma membrane] (Gallus gallus)
IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3:STAT3 [plasma membrane] (Gallus gallus)
IL7R:TSLP:CRLF2:STAT3 [plasma membrane] (Gallus gallus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2:STAT3 [plasma membrane] (Gallus gallus)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 [plasma membrane] (Gallus gallus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Gallus gallus)
STAT3:STAT5A,STAT5B [cytosol] (Gallus gallus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Gallus gallus)
IL4:p-Y-IL4R:JAK2:p-Y-IL2RG:JAK3:p-Y-JAK1:STAT3,STAT6 [plasma membrane] (Gallus gallus)

as an input of

IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Gallus gallus)
IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Gallus gallus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Gallus gallus)
IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Gallus gallus)
IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Gallus gallus)
STAT3 is phosphorylated downstream of active ALK (Gallus gallus)
STAT3 binds activated MET receptor (Gallus gallus)
STAT3 phosphorylation (Gallus gallus)
STAT3,STAT6 bind p-Y-IL4R (Gallus gallus)

as a member of

STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Gallus gallus)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Gallus gallus)
STAT3,STAT5,(STAT3:STAT5) [cytosol] (Gallus gallus)
STAT1, STAT3 [cytosol] (Gallus gallus)
STAT family members [cytosol] (Gallus gallus)

Other forms of this molecule

phospho-STAT3 [nucleoplasm]

phospho-STAT3 [cytosol]

phospho-STAT3 [nucleoplasm]

phospho-STAT3 [cytosol]

phospho-STAT3 [nucleoplasm]

Inferred From

STAT3,STAT6 [cytosol] (Homo sapiens)

STAT3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001026102.1, XP_015155084.1, XP_015155085.1

OpenTargets

ENSG00000168610

PRO

Q6DV79