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CYFIP1 [cytosol]
Stable Identifier
R-GGA-5672575
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
CYFIP1, E1BW56
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate WASPs and WAVEs (Gallus gallus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:branching complex [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2, WASP, N-WASP [plasma membrane] (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Gallus gallus)
p-Y,S,T-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Gallus gallus)
p-Y-WRC [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 binds effectors at the plasma membrane (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC2 GTPase cycle (Gallus gallus)
RAC2 binds effectors at the plasma membrane (Gallus gallus)
RAC2 plasma membrane effectors [cytosol] (Gallus gallus)
WAVE2 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Gallus gallus)
RAC2 plasma membrane effectors [cytosol] (Gallus gallus)
WAVE2 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC3 GTPase cycle (Gallus gallus)
RAC3 binds effectors at the plasma membrane (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
WAVE1 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RAC3:GTP:RAC3 effectors [plasma membrane] (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
WAVE1 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
WAVE2 Regulatory Complex [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RHOG GTPase cycle (Gallus gallus)
RHOG binds effectors at the plasma membrane (Gallus gallus)
RHOG plasma membrane effectors [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Gallus gallus)
RHOG plasma membrane effectors [cytosol] (Gallus gallus)
CYFIP1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BW56
Gene Names
CYFIP1
Reference Genes
ENSEMBL:ENSGALG00000016736
ENSEMBL:ENSGALG00010002835.1 CYFIP1
Other Identifiers
418677
GO:0000340
GO:0000902
GO:0003723
GO:0005737
GO:0005845
GO:0006417
GO:0007010
GO:0007411
GO:0010592
GO:0016601
GO:0023052
GO:0030027
GO:0030032
GO:0030154
GO:0030833
GO:0031175
GO:0031209
GO:0031267
GO:0034330
GO:0043005
GO:0045202
GO:0048471
GO:0048675
GO:0048856
GO:0050877
GO:0050890
GO:0051388
GO:0065003
GO:0097484
GO:0098794
GO:0099563
GO:0099578
GO:1905274
GO:2000601
Gga.7824.1.S1_at
GgaAffx.25048.1.S1_s_at
Participates
as a member of
RAC1 effectors [cytosol] (Gallus gallus)
CYFIP1,CYFIP2 [cytosol] (Gallus gallus)
as a candidate of
RHOG plasma membrane effectors [cytosol] (Gallus gallus)
as a component of
WAVE1 Regulatory Complex [cytosol] (Gallus gallus)
WAVE2 Regulatory Complex [cytosol] (Gallus gallus)
Other forms of this molecule
CYFIP1 [tertiary granule lumen]
CYFIP1 [specific granule lumen]
CYFIP1 [extracellular region]
CYFIP1 [secretory granule lumen]
Inferred From
CYFIP1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000273749
Ensembl
ENSGALT00010006568
,
ENSGALP00010004036
,
ENSGALG00010002835
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