Reactome | phospho-p-Y496-IL10RA [plasma membrane]

phospho-p-Y496-IL10RA [plasma membrane]

Stable Identifier

R-GGA-6784793

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

A0A1D5PP85

Locations in the PathwayBrowser

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Immune System (Gallus gallus)

- Cytokine Signaling in Immune system (Gallus gallus)
  - Signaling by Interleukins (Gallus gallus)
    - Interleukin-10 signaling (Gallus gallus)
      - IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
      - STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
      - p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Gallus gallus)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Gallus gallus)
        
        p-Y-IL10RA [plasma membrane] (Gallus gallus)
        
        phospho-p-Y496-IL10RA [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5PP85

Reference Genes

ENSEMBL:ENSGALG00000032260

Participates

as a member of

p-Y-IL10RA [plasma membrane] (Gallus gallus)

Other forms of this molecule

IL10RA [plasma membrane]

phospho-p-Y446-IL10RA [plasma membrane]

Inferred From

p-Y496-IL10RA [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 496 (in Homo sapiens)

Coordinate

496

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.