Reactome | INTS2 [nucleoplasm]

INTS2 [nucleoplasm]

Stable Identifier

R-GGA-6807448

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

INTS2, F1P1Z0

Locations in the PathwayBrowser

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Gene expression (Transcription) (Gallus gallus)

- RNA Polymerase II Transcription (Gallus gallus)
  - RNA polymerase II transcribes snRNA genes (Gallus gallus)
    - Integrator complex processes the 3' end of snRNA (Gallus gallus)
      - Integrator [nucleoplasm] (Gallus gallus)
        
        INTS2 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS2 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS2 [nucleoplasm] (Gallus gallus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Gallus gallus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS2 [nucleoplasm] (Gallus gallus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Gallus gallus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Gallus gallus)
        
        Integrator [nucleoplasm] (Gallus gallus)
        
        INTS2 [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:F1P1Z0

Gene Names

INTS2

Reference Genes

ENSEMBL:ENSGALG00000005269

ENSEMBL:ENSGALG00010029316.1 INTS2

Other Identifiers

417640

GO:0005634

GO:0016073

GO:0016180

GO:0032039

GO:0034472

GO:0043226

GT_A_87_P036717

Gga.1447.2.S1_s_at

Gga.1447.3.S1_s_at

GgaAffx.12093.1.S1_s_at

Participates

as a component of

Integrator [nucleoplasm] (Gallus gallus)

Inferred From

INTS2 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000108506

Ensembl

ENSGALT00010070901, ENSGALP00010043592, ENSGALG00010029316

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