Reactome | RPL15 [cytosol]

RPL15 [cytosol]

Stable Identifier

R-GGA-72416

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

RPL15, F1NQG5

Locations in the PathwayBrowser

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Metabolism of RNA (Gallus gallus)

- Nonsense-Mediated Decay (NMD) (Gallus gallus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL15 [cytosol] (Gallus gallus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL15 [cytosol] (Gallus gallus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Gallus gallus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL15 [cytosol] (Gallus gallus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Gallus gallus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Gallus gallus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL15 [cytosol] (Gallus gallus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Gallus gallus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Gallus gallus)
        
        80S ribosome [cytosol] (Gallus gallus)
        
        60S ribosomal complex [cytosol] (Gallus gallus)
        
        RPL15 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:F1NQG5

Gene Names

RPL15

Reference Genes

BioGPS Gene:428442 RPL15

ENSEMBL:ENSGALG00000011290

ENSEMBL:ENSGALG00010001698.1 RPL15

KEGG Gene (Gallus gallus):428442 RPL15

Monarch:428442 RPL15

NCBI Gene:428442 RPL15

Reference Transcript

Other Identifiers

428442

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0022625

GO:0022626

GO:0043226

GO:0044391

GO:1990904

GT_Xhyb_Chicken_CN222907_2520

GT_Xhyb_Chicken_CO763819_4723

Gga.4855.1.S1_at

Participates

as a component of

Inferred From

RPL15 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_015137055.1, XP_015137057.1, XP_004939468.1, XP_015137056.1, NP_001292094.1

OpenTargets

ENSG00000174748

Ensembl

ENSGALT00010003897, ENSGALP00010002201, ENSGALG00010001698