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IRS1 [cytosol]
Stable Identifier
R-GGA-74769
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NIJ3
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-7 signaling (Gallus gallus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Gallus gallus)
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ALK (Gallus gallus)
Active ALK dimer binds IRS1 (Gallus gallus)
Active ALK:IRS1 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Active ALK phosphorylates IRS1 (Gallus gallus)
Active ALK:IRS1 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Signaling by Insulin receptor (Gallus gallus)
Insulin receptor signalling cascade (Gallus gallus)
IRS activation (Gallus gallus)
Binding of IRS to insulin receptor (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Phosphorylation of IRS (Gallus gallus)
IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Signaling by LTK (Gallus gallus)
Active LTK binds IRS1 (Gallus gallus)
Active LTK:IRS1 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
Active LTK phosphorylates IRS1 (Gallus gallus)
Active LTK:IRS1 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
IRS1 recruits GRB2 to active LTK (Gallus gallus)
Active LTK:p-Y IRS1:GRB2 [plasma membrane] (Gallus gallus)
IRS1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NIJ3
Reference Genes
ENSEMBL:ENSGALG00000004959
Participates
as an input of
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Gallus gallus)
Active ALK dimer binds IRS1 (Gallus gallus)
Active LTK binds IRS1 (Gallus gallus)
Binding of IRS to insulin receptor (Gallus gallus)
as a component of
IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits:IRS1,IRS2 [plasma membrane] (Gallus gallus)
Active ALK:IRS1 [plasma membrane] (Gallus gallus)
Active LTK:p-Y IRS1:GRB2 [plasma membrane] (Gallus gallus)
Active LTK:IRS1 [plasma membrane] (Gallus gallus)
IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Gallus gallus)
Other forms of this molecule
phospho-p-6Y-IRS1 [plasma membrane]
IRS1 [plasma membrane]
phospho-p-Y-IRS1 [cytosol]
phospho-p-Y-IRS1 [plasma membrane]
Inferred From
IRS1,2 [cytosol]
(Homo sapiens)
IRS1 [cytosol]
(Homo sapiens)
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