Reactome | FEM1C [cytosol]

FEM1C [cytosol]

Stable Identifier

R-GGA-8863167

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

FEM1C, E1C5C6

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Gallus gallus)

- Post-translational protein modification (Gallus gallus)
  - Neddylation (Gallus gallus)
    - AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Gallus gallus)
      - NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)
      - NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
        
        NEDD8-CRL2 E3 ligase complex [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
        
        CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)
      - CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
        
        CRL2 E3 ubiquitin ligase [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
        
        NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Gallus gallus)
        
        NEDD8-CRL2 E3 ligase complex [cytosol] (Gallus gallus)
        
        CUL2-box protein [cytosol] (Gallus gallus)
        
        FEM1C [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1C5C6

Gene Names

FEM1C

Reference Genes

BioGPS Gene:431262 FEM1C

ENSEMBL:ENSGALG00000008204

ENSEMBL:ENSGALG00010001152.1 FEM1C

KEGG Gene (Gallus gallus):431262 FEM1C

Monarch:431262 FEM1C

NCBI Gene:431262 FEM1C

Reference Transcript

Other Identifiers

431262

GO:0000151

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006511

GO:0030163

GO:0031462

GO:0043161

GO:0043226

GO:0060090

GO:0140627

GO:1990756

GT_A_87_P093561

Gga.19731.1.S1_at

Gga.3497.1.S1_at

GgaAffx.5182.1.S1_at

Participates

as a member of

CUL2-box protein [cytosol] (Gallus gallus)

Inferred From

FEM1C [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_015136303.1, XP_015136302.1, XP_015136304.1, XP_004949743.1, XP_428816.3

OpenTargets

ENSG00000145780

Ensembl

ENSGALG00010001152, ENSGALT00010002627, ENSGALP00010001177

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