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Ub-misfolded nascent CFTR [cytosol]
Stable Identifier
R-GGA-8866534
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Gallus gallus)
Macroautophagy (Gallus gallus)
Selective autophagy (Gallus gallus)
Aggrephagy (Gallus gallus)
Parkin transfers Ub to misfolded proteins (Gallus gallus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Gallus gallus)
Ub-Misfolded Proteins [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
PolyUb-Misfolded proteins bind vimentin to form aggresome (Gallus gallus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [microtubule organizing center] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Gallus gallus)
PolyUb-Misfolded Proteins [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6:Dynein complex [microtubule organizing center] (Gallus gallus)
PolyUb-Misfolded Proteins:HDAC6 [cytosol] (Gallus gallus)
PolyUb-Misfolded Proteins [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Gallus gallus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Gallus gallus)
PolyUb-Misfolded Proteins [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Gallus gallus)
Ub-Misfolded Proteins [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
misfolded CFTR is degraded by the 26S proteasome (Gallus gallus)
Ub-misfolded nascent CFTR [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
misfolded CFTR [endoplasmic reticulum membrane]
(Gallus gallus)
Ub [cytosol]
(Gallus gallus)
Participates
as an input of
misfolded CFTR is degraded by the 26S proteasome (Gallus gallus)
as an output of
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
as a component of
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
as a member of
Ub-Misfolded Proteins [cytosol] (Gallus gallus)
PolyUb-Misfolded Proteins [cytosol] (Gallus gallus)
Inferred From
Ub-misfolded nascent CFTR [cytosol]
(Homo sapiens)
PolyUb-misfolded nascent CFTR [cytosol]
(Homo sapiens)
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