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UBA52 [cytosol]
Stable Identifier
R-GGA-939249
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
Ub-48-UBB(1-76), A0A1L1RTM7
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
Regulation of signaling by CBL (Gallus gallus)
CBL ubiquitinates PI3K (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
TNFR2 non-canonical NF-kB pathway (Gallus gallus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated NF-kB activation (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Josephin domain DUBs (Gallus gallus)
ATXN3 deubiquitinates polyUb-PARK2 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
PARK2 autoubiquitinates (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Ovarian tumor domain proteases (Gallus gallus)
OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
TNFAIP3 (A20) ubiquitinates RIPK1 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
USP10 deubiquitinates SNX3, CFTR (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP18 deubiquitinates TAK1:TAB1 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP20, USP33 deubiquitinate ADRB2 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP33 deubiquitinates CCP110,ARRB (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP4 deubiquitinate TRAF2,TRAF6 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP5 cleaves polyubiquitin (Gallus gallus)
USP5:PolyUb [cytosol] (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
USP8 deubiquitinates RNF128 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Regulated Necrosis (Gallus gallus)
RIPK1-mediated regulated necrosis (Gallus gallus)
Regulation of necroptotic cell death (Gallus gallus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
UBA52 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1L1RTM7
Gene Names
UBA52
Reference Genes
ENSEMBL:ENSGALG00000037716
ENSEMBL:ENSGALG00000037716.3 UBA52
Participates
as a member of
K48-Ub [cytosol] (Gallus gallus)
Other forms of this molecule
UBA52 [endocytic vesicle membrane]
UBA52 [endocytic vesicle membrane]
UBA52 [endocytic vesicle membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [mitochondrial outer membrane]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
phospho-UBA52 [nucleoplasm]
phospho-UBA52 [nucleoplasm]
phospho-UBA52 [nucleoplasm]
UBA52 [cytosol]
phospho-UBA52 [cytosol]
phospho-UBA52 [cytosol]
phospho-UBA52 [cytosol]
UBA52 [endosome membrane]
UBA52 [endosome membrane]
UBA52 [endosome membrane]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [cytosol]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
UBA52 [nucleoplasm]
Inferred From
Ub-48-UBB(1-76) [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine at 48 (in Homo sapiens)
Coordinate
48
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
OpenTargets
ENSG00000221983
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