Reactome | SRC [cytosol]

SRC [cytosol]

Stable Identifier

R-GGA-9628701

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

P00523

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P00523 SRC

Gene Names

SRC

Chain

initiator methionine:1, chain:2-533

Reference Genes

BioGPS Gene:396442 SRC

ENSEMBL:ENSGALG00000003855 SRC

KEGG Gene (Gallus gallus):396442 SRC

Monarch:396442 SRC

NCBI Gene:396442 SRC

Reference Transcript

Participates

as a component of

G alpha (i):GTP:SRC-1 [plasma membrane] (Gallus gallus)

Other forms of this molecule

phospho-p-Y416-SRC [cytosol]

Src [cytosol]

MyrG-SRC [plasma membrane]

SRC-1 [plasma membrane]

phospho-p-Y419-SRC [cytosol]

phospho-MyrG,p-Y530-SRC [plasma membrane]

phospho-MyrG-p-Y419-SRC [plasma membrane]

SRC-2 [cytosol]

Inferred From

SRC [cytosol] (Homo sapiens)

Cross References

ZINC - Investigational

SRC_CHICK

RefSeq

NP_990788.2, XP_015151834.1

ZINC - World Drugs

SRC_CHICK

OpenTargets

ENSG00000197122

ZINC - FDA approved

SRC_CHICK

ZINC - Substances

SRC_CHICK

ZINC target

P00523

PRO

P00523

ZINC - Predictions - Purchasable

SRC_CHICK

PDB

6XVO, 7A33, 3FJ5, 3LOK, 6XVM, 4DGG, 7NES, 5TEH, 4LE9, 3SVV, 5J5S, 2OIQ, 5T0P, 3G6G, 3U4W, 3EN4, 7A3D, 4HVW, 7D57, 7A3B, 5SWH, 4MCV, 6HVE, 3OEZ, 4OMP, 3F3W, 4OMO, 1RLP, 1SRL, 3TZ7, 3UQF, 4OMN, 3OF0, 3EL7, 3F3T, 4OMM, 7A39, 1NLP, 5D12, 5ECA, 4LGH, 7WF5, 5D10, 4RTW, 7A34, 5BMM, 5XP5, 3D7T, 7A31, 2QQ7, 5OB2, 3DQW, 3EN6, 3QLF, 5OB0, 1P13, 5K9I, 3G6H, 6XX4, 3EL8, 5SYS, 6XX2, 4OMQ, 3TZ8, 3UQG, 4QT7, 4YBK, 3U51, 4YBJ, 1RLQ, 3F3U, 7A37, 4RTX, 1PRL, 7A35, 6XVN, 4JZ3, 7NET, 3EN7, 7D5O, 7NER, 4FIC, 3QLG, 2QI8, 7A3E, 2QLQ, 7AH3, 6HVF, 7A3C, 1SRM, 4HVU, 7A3A, 3GEQ, 3G5D, 2PTK, 3F3V, 7A38, 5D11, 6L8L, 1F1W, 4RTY, 5XP7, 1PRM, 3DQX, 4U5J, 5EC7, 4AGW, 4RTU, 7A32, 4JZ4, 7A30, 5OB1, 5OAV, 3F6X, 6WIW, 6XX5, 6XX3, 3EN5, 2HWP, 3TZ9, 4HVV, 1F2F, 2HWO, 5I11, 1NLO, 4O2P, 4RTZ, 3D7U, 4OML, 4LGG, 7A36, 4RTV

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41240 CSK	2	CSK [plasma membrane] (R-HSA-180499) CSK [cytosol] (R-HSA-203776)	0.719	7
UniProt:P18433 PTPRA	1	PTPRA [plasma membrane] (R-HSA-388755)	0.59	4
UniProt:Q00944	11	phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-GGA-8874613) phospho-p-Y194,Y397-PTK2 [cytosol] (R-GGA-8874600) phospho-pY-PTK2 [cytosol] (R-GGA-9632393) phospho-p-5Y-PTK2 [cytosol] (R-GGA-5218711) phospho-p-5Y,S732-PTK2 [cytosol] (R-GGA-5229006) phospho-p-6Y,S732-PTK2 [cytosol] (R-GGA-5218694) PTK2(773-1052) [cytosol] (R-GGA-202829) PTK2(1-772) [cytosol] (R-GGA-202827) PTK2 [cytosol] (R-GGA-201621) phospho-p-Y397-PTK2 [cytosol] (R-GGA-354068) phospho-p-6Y-PTK2 [cytosol] (R-GGA-354128)	0.589	3
UniProt:O88703	1	HCN2 [plasma membrane] (R-MMU-977502)	0.581	5
UniProt:Q9QWY8-1 ASAP1			0.581	3
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.564	2
UniProt:Q90738 AFAP1			0.564	3
UniProt:Q9Y4D1 DAAM1	1	DAAM1 [cytosol] (R-HSA-351052)	0.556	3
UniProt:P61980	2	Hnrnpk [nucleoplasm] (R-RNO-4570532) Hnrnpk [nucleoplasm] (R-RNO-71945)	0.544	2
UniProt:Q9QWY8-2 ASAP1			0.544	2
UniProt:P18052	1	PTPRA [plasma membrane] (R-MMU-388755)	0.525	2

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