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SPSB4 [cytosol]
Stable Identifier
R-GGA-976048
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SPSB2, A0A1D5NUQ3
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Neddylation (Gallus gallus)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Gallus gallus)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL5 E3 ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
CRL E3 ubiquitin ligases [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Gallus gallus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
CRL5 E3 ubiquitin ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Gallus gallus)
NEDD8-CRL5 E3 ligase [cytosol] (Gallus gallus)
CUL5-box protein [cytosol] (Gallus gallus)
SPSB4 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5NUQ3
Gene Names
SPSB4
Reference Genes
ENSEMBL:ENSGALG00000032053
ENSEMBL:ENSGALG00010025297.1 SPSB4
Reference Transcript
RefSeq:XM_015277048.1 SPSB4
RefSeq:XM_426685.4 SPSB4
Other Identifiers
429129
GO:0005515
GO:0005737
GO:0005829
GO:0006511
GO:0016567
GO:0019005
GO:0023052
GO:0030163
GO:0035556
GO:0036211
GO:0042752
GO:0043161
GO:0060090
GO:1902916
GO:1990756
GT_A_87_P077211
GT_A_87_P163798
GgaAffx.11134.1.S1_at
Participates
as a member of
CUL5-box protein [cytosol] (Gallus gallus)
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
Other forms of this molecule
SPSB4 [cytosol]
Inferred From
SPSB2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_426685.2
,
XP_015132534.1
OpenTargets
ENSG00000175093
Ensembl
ENSGALG00010025297
,
ENSGALT00010061747
,
ENSGALP00010038116
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