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MX2 [cytosol]
Stable Identifier
R-HSA-1015675
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
MXA, Interferon-induced GTP-binding protein Mx2, MX2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
ISGylation of host proteins (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
Mx GTPases [cytosol] (Homo sapiens)
MX2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P20592 MX2
Gene Names
MX2
Chain
chain:1-715
Reference Genes
BioGPS Gene:4600 MX2
COSMIC (genes):MX2 MX2
CTD Gene:4600 MX2
dbSNP Gene:4600 MX2
ENSEMBL:ENSG00000183486 MX2
HGNC:7533 MX2
KEGG:hsa:4600 MX2
Monarch:4600 MX2
NCBI Gene:4600 MX2
OMIM:147890 MX2
UCSC:P20592 MX2
Reference Transcript
RefSeq:XM_005260983.4 MX2
RefSeq:XM_005260984.1 MX2
RefSeq:XM_011529571.1 MX2
RefSeq:XM_011529572.1 MX2
RefSeq:NM_002463.1 MX2
Other Identifiers
11726479_a_at
11753064_a_at
204994_PM_at
204994_at
3922038
3922039
3922040
3922041
3922042
3922043
3922044
3922045
3922046
3922047
3922050
3922051
3922054
3922055
3922056
3922057
3922058
3922059
3922062
3922067
3922071
3922072
3922073
3922074
3922075
3922076
3922077
3922078
3922079
3922080
3922081
3922082
3922083
3922084
3922085
3922086
3922087
3922088
3922089
3922090
3922091
3922092
3922093
3922126
4600
73776_at
8068697
879_at
89899_at
A_14_P119360
A_23_P6263
A_24_P117294
A_33_P3278200
GE57916
GO:0002376
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005634
GO:0005643
GO:0005737
GO:0005829
GO:0005874
GO:0006952
GO:0008017
GO:0008092
GO:0009615
GO:0015031
GO:0016020
GO:0016787
GO:0035455
GO:0043226
GO:0045087
GO:0046822
GO:0051028
GO:0051607
GO:0051726
GO:0098542
HMNXSV003001288
HMNXSV003025940
ILMN_2231928
M30818_at
PH_hs_0000117
TC21000188.hg
g11342663_3p_at
Participates
as a member of
Mx GTPases [cytosol] (Homo sapiens)
Inferred To
MX2 [cytosol]
(Bos taurus)
MX2 [cytosol]
(Canis familiaris)
MX2 [cytosol]
(Dictyostelium discoideum)
MX2 [cytosol]
(Plasmodium falciparum)
MX2 [cytosol]
(Sus scrofa)
Homologues of MX2 [cytosol]
(Dictyostelium discoideum)
Homologues of MX2 [cytosol]
(Plasmodium falciparum)
Homologues of MX2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
XP_005261041.1
,
NP_002454.1
,
XP_011527873.1
,
XP_005261040.1
,
XP_011527874.1
ENSEMBL
ENST00000680862
,
ENST00000418103
,
ENSP00000506423
,
ENST00000330714
,
ENST00000435611
,
ENSP00000410188
,
ENSP00000333657
,
ENSP00000389256
OpenTargets
ENSG00000183486
HPA
ENSG00000183486-MX2
PRO
P20592
Pharos - Targets
P20592
PDB
4WHJ
,
5UOT
,
4X0R
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96KQ7 EHMT2
1
EHMT2 [nucleoplasm]
(R-HSA-212151)
0.556
3
UniProt:O75928 PIAS2
1
PIAS2 [nucleoplasm]
(R-HSA-2993787)
0.556
3
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