Reactome | OASL [cytosol]

OASL [cytosol]

Stable Identifier

R-HSA-1015678

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

59 kDa 2'-5'-oligoadenylate synthase-like protein, OASL_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q13601 KRR1

Expand all

Immune System (Homo sapiens)

- Cytokine Signaling in Immune system (Homo sapiens)
  - Interferon Signaling (Homo sapiens)
    - Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
      - OAS antiviral response (Homo sapiens)
        
        OASL binds DDX58 (Homo sapiens)
        
        OASL [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q15646 OASL

Gene Names

OASL, TRIP14

Chain

initiator methionine:, chain:2-514

Reference Genes

BioGPS Gene:8638 OASL

COSMIC (genes):OASL OASL

CTD Gene:8638 OASL

dbSNP Gene:8638 OASL

ENSEMBL:ENSG00000135114 OASL

HGNC:8090 OASL

KEGG:hsa:8638 OASL

Monarch:8638 OASL

NCBI Gene:8638 OASL

OMIM:603281 OASL

UCSC:Q15646 OASL

Reference Transcript

Other Identifiers

11726364_x_at

16771417

205660_PM_at

205660_at

210797_PM_s_at

210797_s_at

269_at

34491_at

3474826

3474827

3474828

3474830

3474832

3474833

3474834

3474835

3474837

3474838

3474839

3474840

3474841

3474842

3474843

3474844

3474845

3474846

7967117

8638

A_23_P139786

GE55258

GO:0002376

GO:0003677

GO:0003723

GO:0003725

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0009615

GO:0016020

GO:0016740

GO:0016779

GO:0043226

GO:0045071

GO:0045087

GO:0046966

GO:0051607

GO:0060337

GO:0070106

GO:0098542

GO:0140374

GO:1900246

HMNXSV003030381

ILMN_1674811

ILMN_1681721

L40387_at

PH_hs_0029118

TC12002059.hg

g11321576_3p_at

g4731858_3p_a_at

Participates

as a component of

OASL:DDX58 [cytosol] (Homo sapiens)

as an input of

OASL binds DDX58 (Homo sapiens)

as a member of

OAS proteins [cytosol] (Homo sapiens)

Inferred To

Oasl1 [cytosol] (Canis familiaris)

Oasl1 [cytosol] (Mus musculus)

OASL [cytosol] (Bos taurus)

OASL [cytosol] (Gallus gallus)

OASL [cytosol] (Sus scrofa)

Oasl [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_003724.1, XP_016875630.1, NP_001382347.1, NP_937856.1, NP_001248754.1

OpenTargets

ENSG00000135114

ENSEMBL

ENST00000620239, ENST00000339275, ENSP00000444127, ENST00000257570, ENSG00000135114, ENSP00000257570, ENST00000543677, ENSP00000341125, ENSP00000479512

HPA

ENSG00000135114-OASL

GeneCards

OASL

PRO

Q15646

Pharos - Targets

Q15646

PDB

1WH3, 4XQ7

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q4G0J3 LARP7			0.623	3
UniProt:Q9H7B2 RPF2			0.527	2
UniProt:Q7Z2W4 ZC3HAV1	2	ZC3HAV1(2-624)-BRAF(439-766) fusion [cytosol] (R-HSA-6802506) ZC3HAV1(2-624)-p-BRAF(439-766) fusion [cytosol] (R-HSA-6802557)	0.527	2
UniProt:Q13601 KRR1	1	KRR1 [nucleoplasm] (R-HSA-6790611)	0.527	2
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [extracellular region] (R-HSA-9017791) YBX1 [nucleoplasm] (R-HSA-72041)	0.527	2
UniProt:O15226 NKRF			0.527	2
UniProt:Q9GZR7 DDX24			0.527	2
UniProt:Q9BQ39 DDX50			0.527	2
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	2
UniProt:Q8N9T8 KRI1			0.527	2
UniProt:Q96GQ7 DDX27			0.527	2
UniProt:P16989 YBOX3			0.527	2
UniProt:Q9NW13 RBM28	1	RBM28 [nucleoplasm] (R-HSA-6791192)	0.527	3
UniProt:Q9GZR2 REXO4			0.527	2
UniProt:Q99575 POP1	1	POP1 [nucleoplasm] (R-HSA-5696802)	0.527	2
UniProt:Q8TDD1 DDX54			0.527	2
UniProt:Q9HCE1 MOV10	1	MOV10 [cytosol] (R-HSA-427772)	0.527	2
UniProt:Q9UL40 ZN346			0.527	2
UniProt:Q15397 PUM3			0.527	2
UniProt:Q9H6S0 YTHDC2	1	YTHDC2 [nucleoplasm] (R-HSA-9935827)	0.527	2
UniProt:Q6P158 DHX57			0.527	2
UniProt:P39019 RPS19	2	RPS19 [cytosol] (R-HSA-72343) RPS19 [nucleoplasm] (R-HSA-6798710)	0.527	2
UniProt:Q9NUL3 STAU2			0.527	2

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