Reactome | IFITM3 [plasma membrane]

IFITM3 [plasma membrane]

Stable Identifier

R-HSA-1015688

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Interferon-induced transmembrane protein 3, IFM3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q6UWN5 LYPD5

Expand all

External Reference Information

External Reference

UniProt:Q01628 IFITM3

Gene Names

IFITM3

Chain

chain:1-133

Reference Genes

BioGPS Gene:10410 IFITM3

COSMIC (genes):IFITM3 IFITM3

CTD Gene:10410 IFITM3

dbSNP Gene:10410 IFITM3

ENSEMBL:ENSG00000142089 IFITM3

HGNC:5414 IFITM3

KEGG:hsa:10410 IFITM3

Monarch:10410 IFITM3

NCBI Gene:10410 IFITM3

OMIM:605579 IFITM3

UCSC:Q01628 IFITM3

Reference Transcript

RefSeq:NM_021034.2 IFITM3

Other Identifiers

10410

11715239_x_at

16733851

212203_PM_x_at

212203_x_at

3315667

3315668

3315669

3315670

3315674

3315676

3315677

3315683

3357843

3357844

3357845

3357846

3357847

3357848

3357849

3357850

3357851

3357852

3357853

3357858

3357859

3357861

3357863

3357865

3357867

3357869

3357870

3357871

3357873

3357875

3357877

41745_at

676_g_at

7945371

A_23_P87545

GE82581

GO:0002376

GO:0005515

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005773

GO:0005886

GO:0006955

GO:0009615

GO:0016020

GO:0031410

GO:0031901

GO:0031902

GO:0032897

GO:0032991

GO:0034341

GO:0035455

GO:0035456

GO:0043226

GO:0045071

GO:0045087

GO:0046597

GO:0048471

GO:0051607

GO:0060337

GO:0098542

HMNXSV003042131

Hs.182241.2.S1_3p_x_at

ILMN_1805750

TC11001230.hg

X57351_s_at

p2139

Participates

as an output of

Expression of IFN-induced genes (Homo sapiens)

Cross References

ENSEMBL

ENSP00000382707, ENST00000399808, ENSG00000142089

OpenTargets

ENSG00000142089

GeneCards

IFITM3

HPA

ENSG00000142089-IFITM3

PRO

Q01628

Pharos - Targets

Q01628

GlyGen

Q01628

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H6H4 REEP4			0.666	4
UniProt:Q86VR2 RETR3			0.666	4
UniProt:P43628 KIR2DL3	1	KIR2DL3 [plasma membrane] (R-HSA-3006532)	0.556	3
UniProt:Q6UWN5 LYPD5	2	cleaved GPI-LYPD5 [extracellular region] (R-HSA-8941140) GPI-LYPD5 [plasma membrane] (R-HSA-8940779)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:O60669 SLC16A7	1	SLC16A7 [plasma membrane] (R-HSA-373955)	0.556	3
UniProt:Q96HJ5 MS4A3	2	MS4A3 [plasma membrane] (R-HSA-6806321) MS4A3 [specific granule membrane] (R-HSA-6799514)	0.556	3
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:P60201-2 PLP1			0.556	3
UniProt:O95870 ABHGA			0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:P19397 CD53	3	CD53 [specific granule membrane] (R-HSA-6804793) CD53 [plasma membrane] (R-HSA-6804817) CD53 [tertiary granule membrane] (R-HSA-6804799)	0.556	3
UniProt:P35372-10 OPRM1			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q9Y680 FKBP7			0.556	3
UniProt:Q9NZD1 GPC5D			0.556	3
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.556	3
UniProt:Q12908 SLC10A2	1	SLC10A2 [plasma membrane] (R-HSA-194173)	0.556	3
UniProt:Q9NXB9 ELOVL2	1	ELOVL2 [endoplasmic reticulum membrane] (R-HSA-548677)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:O95415 BRI3	2	BRI3 [plasma membrane] (R-HSA-6806260) BRI3 [azurophil granule membrane] (R-HSA-6799127)	0.543	6
UniProt:P43490 NAMPT	1	NAMPT [cytosol] (R-HSA-197188)	0.508	3