PXLP-K391-ALAS2 [mitochondrial matrix]

Stable Identifier
R-HSA-1022083
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
5-aminolevulinate synthase, erythroid (pyridoxal phosphate cofactor), 5-aminolevulinate synthase, erythroid-specific, mitochondrial precursor, HEM0_HUMAN, ALAS2
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P22557 ALAS2
Gene Names
ALAS2, ALASE, ASB
Chain
transit peptide:1-49, chain:50-587
Reference Genes
BioGPS Gene:212 ALAS2
COSMIC (genes):ALAS2 ALAS2
CTD Gene:212 ALAS2
dbSNP Gene:212 ALAS2
ENSEMBL:ENSG00000158578 ALAS2
HGNC:397 ALAS2
KEGG:hsa:212 ALAS2
Monarch:212 ALAS2
NCBI Gene:212 ALAS2
OMIM:301300 ALAS2
UCSC:P22557 ALAS2
Reference Transcript
Other Identifiers
11734745_a_at
11738208_a_at
11758412_s_at
17111520
211560_PM_s_at
211560_s_at
212
37285_at
4009851
4009852
4009854
4009855
4009858
4009859
4009861
4009862
4009863
4009864
4009865
4009866
4009868
4009872
4009873
4009874
4009876
8173135
A_32_P22654
A_32_P385587
GE59859
GO:0001666
GO:0003824
GO:0003870
GO:0005515
GO:0005739
GO:0005743
GO:0005759
GO:0006778
GO:0006782
GO:0006783
GO:0006879
GO:0009058
GO:0016740
GO:0016746
GO:0030154
GO:0030170
GO:0030218
GO:0032364
GO:0033014
GO:0042541
GO:0043226
GO:0048821
GO:0048856
HMNXSV003056201
ILMN_1708323
ILMN_2271875
ILMN_2367126
PH_hs_0025784
TC0X001077.hg
Z83821_cds2_at
g11493529_3p_s_at
Participates
as a component of
Inferred To
Alas [mitochondrial matrix] (Drosophila melanogaster)
ALAS2 [mitochondrial matrix] (Canis familiaris)
ALAS2 [mitochondrial matrix] (Sus scrofa)
Homologues of PXLP-K391-ALAS2 [mitochondrial matrix] (Rattus norvegicus)
hemA [mitochondrial matrix] (Dictyostelium discoideum)
PXLP-K391-ALAS2 [mitochondrial matrix] (Bos taurus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Danio rerio)
PXLP-K391-ALAS2 [mitochondrial matrix] (Mus musculus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Plasmodium falciparum)
PXLP-K391-ALAS2 [mitochondrial matrix] (Rattus norvegicus)
PXLP-K391-ALAS2 [mitochondrial matrix] (Saccharomyces cerevisiae)
PXLP-K391-ALAS2 [mitochondrial matrix] (Schizosaccharomyces pombe)
alas2 [mitochondrial matrix] (Xenopus tropicalis)
Alas2 [mitochondrial matrix] (Rattus norvegicus)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 391
Coordinate
391
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q8N9N5 BANP  1 0.556 3
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