Reactome | OS9 [endoplasmic reticulum membrane]

OS9 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1022132

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Protein OS-9, OS9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13438 OS9

Gene Names

OS9

Chain

signal peptide:1-25, chain:26-667

Reference Genes

BioGPS Gene:10956 OS9

COSMIC (genes):OS9 OS9

CTD Gene:10956 OS9

dbSNP Gene:10956 OS9

ENSEMBL:ENSG00000135506 OS9

HGNC:16994 OS9

KEGG:hsa:10956 OS9

Monarch:10956 OS9

NCBI Gene:10956 OS9

OMIM:609677 OS9

UCSC:Q13438 OS9

Reference Transcript

Other Identifiers

10956

11718989_s_at

11718990_x_at

11751704_a_at

11752346_a_at

11752347_x_at

11752689_a_at

11753934_at

1555907_PM_at

1555907_at

16753125

16753158

200714_PM_x_at

200714_x_at

215399_PM_s_at

215399_s_at

237175_PM_at

237175_at

3418437

3418438

3418440

3418441

3418442

3418443

3418444

3418445

3418447

3418450

3418451

3418452

3418453

3418454

3418455

3418456

3418457

3418458

3418459

3418460

3418461

3418462

3418463

3418464

3418465

3418466

3418467

3418468

3418469

3418470

3418471

3418472

3418473

3418474

3418475

3418476

3418477

3418482

3418484

3418491

36996_at

72866_at

7956593

84062_at

86119_at

87781_s_at

ADDON002340.hg

A_14_P112435

A_14_P129207

A_14_P137588

A_24_P270166

A_24_P417935

GE530514

GE739476

GE753288

GE829630

GO:0000836

GO:0002020

GO:0005515

GO:0005783

GO:0005788

GO:0005789

GO:0006511

GO:0006605

GO:0006621

GO:0006886

GO:0016567

GO:0030163

GO:0030246

GO:0030968

GO:0030970

GO:0034976

GO:0036503

GO:0043226

GO:1904153

HMNXSV003023758

HMNXSV003038094

Hs.223908.0.A1_3p_at

Hs.76228.2.A1_3p_s_at

Hs2.302435.1.S1_3p_at

ILMN_2361807

PH_hs_0004399

TC12000539.hg

TC12002401.hg

U41635_at

p34008

Participates

as a member of

OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Homo sapiens)

as a component of

OS9:SEL1:ERAD E3 ligases:DERL2 [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

OS9 [endoplasmic reticulum membrane] (Bos taurus)

OS9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

OS9 [endoplasmic reticulum membrane] (Canis familiaris)

OS9 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

OS9 [endoplasmic reticulum membrane] (Mus musculus)

OS9 [endoplasmic reticulum membrane] (Rattus norvegicus)

OS9 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

OS9 [endoplasmic reticulum membrane] (Sus scrofa)

os9 [endoplasmic reticulum membrane] (Danio rerio)

os9 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000135506

ENSEMBL

ENST00000439210, ENSP00000373794, ENST00000257966, ENSP00000389632, ENST00000315970, ENST00000552285, ENSP00000407360, ENSP00000318165, ENSP00000373798, ENST00000389146, ENST00000551035, ENSP00000257966, ENSP00000447866, ENST00000389142, ENST00000435406, ENSP00000450010

HPA

ENSG00000135506-OS9

PRO

Q13438

Pharos - Targets

Q13438

GlyGen

Q13438

PDB

3AIH

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBV2 SEL1L	1	SEL1L [endoplasmic reticulum membrane] (R-HSA-1911545)	0.864	14
UniProt:Q86TM6 SYVN1	1	SYVN1(1-617) [endoplasmic reticulum membrane] (R-HSA-535496)	0.69	10
UniProt:Q16665 HIF1A	7	HIF1A [nucleoplasm] (R-HSA-1234135) HIF1A [cytosol] (R-HSA-1234102) p-Y565-HIF1A [cytosol] (R-HSA-8857584) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) 2xHP-HIF1A [cytosol] (R-HSA-1234131) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105) HN-HIF1A [cytosol] (R-HSA-1234110)	0.649	9
UniProt:P14625 HSP90B1	4	HSP90B1 [endocytic vesicle lumen] (R-HSA-3221623) HSP90B1 [extracellular region] (R-HSA-3221653) p-HSP90B1 [endoplasmic reticulum lumen] (R-HSA-8957016) HSP90B1 [endoplasmic reticulum lumen] (R-HSA-981545)	0.643	5
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.623	3
UniProt:Q8NCR0 B3GALNT2	1	B3GALNT2 [endoplasmic reticulum membrane] (R-HSA-8878916)	0.527	4
UniProt:P54764 EPHA4	2	p-Y596,Y602-EPHA4 [plasma membrane] (R-HSA-3928352) EPHA4 [plasma membrane] (R-HSA-2682325)	0.527	3
UniProt:Q92673 SORL1	2	SORL1 [endosome membrane] (R-HSA-8871475) SORL1 [Golgi membrane] (R-HSA-8871510)	0.527	3
UniProt:O00468 AGRN	20	HS(4)-AGRN [plasma membrane] (R-HSA-2076654) HS(6)-AGRN [plasma membrane] (R-HSA-2076678) HS(2)-AGRN [plasma membrane] (R-HSA-2076686) HS(1)-AGRN [plasma membrane] (R-HSA-2076634) HS(3)-AGRN [plasma membrane] (R-HSA-2076663) HS(5)-AGRN [plasma membrane] (R-HSA-2076642) AGRN(30-2045) [extracellular region] (R-HSA-375056) XylS-AGRN(30-2045) [Golgi lumen] (R-HSA-2064220) Gal-Xyl-AGRN [Golgi lumen] (R-HSA-2064130) AGRN(30-2045) [Golgi lumen] (R-HSA-2054104) Gal-Gal-Xyl-AGRN [Golgi lumen] (R-HSA-2064040) GlcA-Gal-Gal-Xyl-AGRN [Golgi lumen] (R-HSA-2064200) HS(3)-AGRN [Golgi lumen] (R-HSA-2076493) HS(4)-AGRN [Golgi lumen] (R-HSA-2076337) HS(2)-AGRN [Golgi lumen] (R-HSA-2076521) HS(1)-AGRN [Golgi lumen] (R-HSA-2076350) Heparan(4)-AGRN [Golgi lumen] (R-HSA-2076300) Heparan(3)-AGRN [Golgi lumen] (R-HSA-2076569) Heparan(2)-AGRN [Golgi lumen] (R-HSA-2076301) Heparan(1)-AGRN [Golgi lumen] (R-HSA-2076317)	0.527	3
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2
UniProt:P01008 SERPINC1	8	SERPINC1 [endoplasmic reticulum lumen] (R-HSA-8956773) p-SERPINC1 [endoplasmic reticulum lumen] (R-HSA-8957069) SERPINC1(426-464) [extracellular region] (R-HSA-140817) SERPINC1(33-425) [extracellular region] (R-HSA-140814) SERPINC1 [extracellular region] (R-HSA-140807) SERPINC1 [plasma membrane] (R-HSA-140792) SERPINC1(426-464) [plasma membrane] (R-HSA-140816) SERPINC1(33-425) [plasma membrane] (R-HSA-140815)	0.527	3
UniProt:P18850 ATF6	7	ATF6(1-380) [nucleoplasm] (R-HSA-381211) ATF6(420-670) [Golgi membrane] (R-HSA-420814) ATF6(380-419) [Golgi membrane] (R-HSA-420817) ATF6(1-380) [cytosol] (R-HSA-381075) ATF6(1-419) [Golgi membrane] (R-HSA-420815) ATF6 [Golgi membrane] (R-HSA-381000) ATF6 [endoplasmic reticulum membrane] (R-HSA-381222)	0.527	3
UniProt:P04578 env	7	ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Surface protein gp120 (P04578) [cytosol] (R-HIV-189269)	0.462	2