Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA

Stable Identifier
R-HSA-109343
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA
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The second of the two accessory enzymes, 2,4-dienoyl-CoA reductase catalyses an oxidation-reduction (redox) reaction to yield 3-trans-decenoyl-CoA.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Beaudet, AL, Scriver, CR, Sly, WS, Valle, D

  2001
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Catalyst Activity

oxidoreductase activity, acting on NAD(P)H of DECR1 tetramer [mitochondrial matrix]

Physical Entity
DECR1 tetramer [mitochondrial matrix] (Homo sapiens)
Activity
oxidoreductase activity, acting on NAD(P)H (GO:0016651)
Orthologous Events
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Bos taurus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Caenorhabditis elegans)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Canis familiaris)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Danio rerio)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Gallus gallus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Mus musculus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Rattus norvegicus)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Sus scrofa)
Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Xenopus tropicalis)
Authored
Gillespie, ME  (2004-01-19)
Created
Gillespie, ME  (2004-01-02)
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