Reactome | AMP + H2O => adenosine + orthophosphate [NT5C1B]

AMP + H2O => adenosine + orthophosphate [NT5C1B]

Stable Identifier

R-HSA-109415

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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AMP + H2O => adenosine + orthophosphate [NT5C1B]

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5'-nucleotidase cytosolic IB catalyzes the hydrolysis of AMP to yield adenosine and orthophosphate. The human enzyme has been identified as the product of a recombinant DNA clone, but its biochemical properties are largely inferred from those of the better studied mouse and rat enzymes (Sala-Newby and Newby 2001; Sala-Newby et al. 2003).

Literature References

PubMed ID	Title	Journal	Year
12750059	Metabolic and functional consequences of cytosolic 5'-nucleotidase-IA overexpression in neonatal rat cardiomyocytes Newby, AC, Sala-Newby, GB, Freeman, NV, Curto, MA	Am J Physiol Heart Circ Physiol	2003
11690631	Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein Newby, AC, Sala-Newby, GB	Biochim Biophys Acta	2001