Reactome | Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA

Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA

Stable Identifier

R-HSA-111438

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA

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The U7 snRNP. This particle contains the U7 snRNA, the smallest of the snRNAs which varies from 57-70 nts long depending on the species. The 5’ end of U7 snRNA binds to a sequence 3’ of the stemloop, termed the histone downstream element (HDE). There are a number of proteins found in the U7 snRNP. There are 7 Sm proteins, as are present in the spliceosomal snRNP. Five of these proteins are the same as ones found in the spliceosomal snRNPs and there are 2, Lsm10 and Lsm11 that are unique to U7 snRNP.

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