PDE4A,C,D hydrolyse cAMP

Stable Identifier
R-HSA-111962
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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PDE4A,C,D hydrolyse cAMP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
cAMP-specific 3',5'-cyclic phosphodiesterases (PDE4A-D) hydrolyze cAMP to AMP (Huston et al. 1997).
Literature References
PubMed ID Title Journal Year
9371714 Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3

Steele, MR, Huston, E, Bolger, GB, Perry, MJ, Russell, A, Owens, RJ, Ross, AH, Lumb, S, Houslay, MD, Catterall, C

Biochem J 1997
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Output
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as an event of
Catalyst Activity

3',5'-cyclic-AMP phosphodiesterase activity of PDE4A,C,D [cytosol]

Physical Entity
PDE4A,C,D [cytosol] (Homo sapiens)
Activity
3',5'-cyclic-AMP phosphodiesterase activity (GO:0004115)
Orthologous Events
PDE4A,C,D hydrolyse cAMP (Bos taurus)
PDE4A,C,D hydrolyse cAMP (Caenorhabditis elegans)
PDE4A,C,D hydrolyse cAMP (Canis familiaris)
PDE4A,C,D hydrolyse cAMP (Dictyostelium discoideum)
PDE4A,C,D hydrolyse cAMP (Drosophila melanogaster)
PDE4A,C,D hydrolyse cAMP (Gallus gallus)
PDE4A,C,D hydrolyse cAMP (Mus musculus)
PDE4A,C,D hydrolyse cAMP (Plasmodium falciparum)
PDE4A,C,D hydrolyse cAMP (Rattus norvegicus)
PDE4A,C,D hydrolyse cAMP (Sus scrofa)
PDE4A,C,D hydrolyse cAMP (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Schmidt, EE  (2004-03-26)
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