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Neurotransmitter receptors and postsynaptic signal transmission
Stable Identifier
R-HSA-112314
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
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The neurotransmitter in the synaptic cleft released by the pre-synaptic neuron binds specific receptors located on the post-synaptic terminal. These receptors are either ion channels or G protein coupled receptors that function to transmit the signals from the post-synaptic membrane to the cell body.
Participants
Events
Acetylcholine binding and downstream events
(Homo sapiens)
Glutamate binding, activation of AMPA receptors and synaptic plasticity
(Homo sapiens)
Activation of NMDA receptors and postsynaptic events
(Homo sapiens)
Activation of kainate receptors upon glutamate binding
(Homo sapiens)
GABA receptor activation
(Homo sapiens)
GLRA:GLRB:Gly transports extracellular Cl- to cytosol
(Homo sapiens)
NBEA binds GLRB
(Homo sapiens)
HTR3 pentamers:5HT transport Na+,K+,Ca2+
(Homo sapiens)
HTR3A pentamer binds 5HT
(Homo sapiens)
HTR3A pentamer:5HT transports Na+,K+,Ca2+
(Homo sapiens)
HTR3A antagonists bind HTR3A pentamer
(Homo sapiens)
Participates
as an event of
Transmission across Chemical Synapses (Homo sapiens)
Event Information
Go Biological Process
chemical synaptic transmission (0007268)
Orthologous Events
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
Neurotransmitter receptors and postsynaptic signal transmission (Dictyostelium discoideum)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
Neurotransmitter receptors and postsynaptic signal transmission (Plasmodium falciparum)
Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
Neurotransmitter receptors and postsynaptic signal transmission (Saccharomyces cerevisiae)
Neurotransmitter receptors and postsynaptic signal transmission (Schizosaccharomyces pombe)
Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
Neurotransmitter receptors and postsynaptic signal transmission (Xenopus tropicalis)
Authored
Mahajan, SS (2008-01-14)
Reviewed
Restituito, S (2008-12-02)
Kavalali, E (2008-12-02)
Created
Joshi-Tope, G (2004-04-22)
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