Reactome | NELFCD [nucleoplasm]

NELFCD [nucleoplasm]

Stable Identifier

R-HSA-112428

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

NELF-C/D protein, Negative elongation factor C/D, NELF-C/D, TH1-like protein, HSPC130

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8IXH7 NELFCD

Gene Names

NELFCD, NELFD, TH1, TH1L, HSPC130

Chain

chain:1-590

Reference Genes

BioGPS Gene:51497 NELFCD

COSMIC (genes):NELFCD NELFCD

CTD Gene:51497 NELFCD

dbSNP Gene:51497 NELFCD

ENSEMBL:ENSG00000101158 NELFCD

HGNC:15934 NELFCD

KEGG Gene (Homo sapiens):51497 NELFCD

Monarch:51497 NELFCD

NCBI Gene:51497 NELFCD

OMIM:605297 NELFCD

UCSC:Q8IXH7 NELFCD

Reference Transcript

RefSeq:NM_198976.2 NELFCD

Other Identifiers

0003450040

0006420286

11739446_a_at

11747270_a_at

11754439_x_at

16915364

220607_PM_x_at

220607_x_at

225006_PM_x_at

225006_x_at

225261_PM_x_at

225261_x_at

225865_PM_x_at

225865_x_at

3891280

3891281

3891282

3891283

3891285

3891286

3891288

3891289

3891290

3891293

3891295

3891298

3891299

3891301

3891303

3891305

3891307

3891308

3891309

3891310

3891314

3891315

3891317

3891318

3891319

3891320

3891321

3891322

3891323

51497

8063697

A_14_P108400

A_23_P210643

GE55265

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0008150

GO:0009058

GO:0016020

GO:0032021

GO:0032991

GO:0034244

GO:0034641

GO:0043226

GO:0045892

HMNXSV003048914

Hs.5184.1.A1_3p_a_at

ILMN_1663954

ILMN_1711450

TC20000467.hg

Participates

as a component of

as an input of

Formation of NELF complex (Homo sapiens)

Inferred To

Nelfcd [nucleoplasm] (Mus musculus)

Nelfcd [nucleoplasm] (Rattus norvegicus)

nelfcd [nucleoplasm] (Danio rerio)

nelfcd [nucleoplasm] (Xenopus tropicalis)

TH1 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of NELFCD [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of NELFCD [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of NELFCD [nucleoplasm] (Schizosaccharomyces pombe)

NELFCD [nucleoplasm] (Bos taurus)

NELFCD [nucleoplasm] (Canis familiaris)

NELFCD [nucleoplasm] (Dictyostelium discoideum)

NELFCD [nucleoplasm] (Gallus gallus)

NELFCD [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_945327.2

OpenTargets

ENSG00000101158

HPA

ENSG00000101158-NELFCD

GeneCards

Q8IXH7

Ensembl

ENSG00000101158, ENST00000652272, ENSP00000499018

PRO

Q8IXH7

Pharos - Targets

Q8IXH7

PDB

5L3X, 6GML

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H3P2 NELFA	1	NELFA [nucleoplasm] (R-HSA-112426)	0.831	12
UniProt:A0A1U9X8X8 A0A1U9X8X8			0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:Q8WX92-2 Q8WX922			0.556	3
UniProt:P10398 ARAF	4	p-S299,S302,T452,T455,S576 ARAF [cytosol] (R-HSA-5672646) p-S299,S302,T452,T455,S576 ARAF [plasma membrane] (R-HSA-5672648) p-S576 ARAF [cytosol] (R-HSA-5672681) p-S214,S576 ARAF [cytosol] (R-HSA-5672639)	0.553	5

Cite Us!