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RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
Stable Identifier
R-HSA-114540
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Homo sapiens)
PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activator:PI3K [plasma membrane] (Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Homo sapiens)
RAC1,RAC2,RHOG activate PI3K (Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Homo sapiens)
Participants
components
PI3K alpha [cytosol]
(Homo sapiens)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane]
(Homo sapiens)
Participates
as an output of
RAC1,RAC2,RHOG activate PI3K (Homo sapiens)
as a member of
Activator:PI3K [plasma membrane] (Homo sapiens)
Inferred To
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Bos taurus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Caenorhabditis elegans)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Canis familiaris)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Gallus gallus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Mus musculus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Rattus norvegicus)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Sus scrofa)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane]
(Xenopus tropicalis)
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