PTP1B dephosphorylates GHR

Stable Identifier
R-HSA-1169192
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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PTP1B induces the dephosphorylation of GHR (Pasquali et al. 2003).
Literature References
PubMed ID Title Journal Year
12907755 Identification of protein tyrosine phosphatases with specificity for the ligand-activated growth hormone receptor

Hooft van Huijsduijnen, R, Arigoni, F, Pasquali, C, Curchod, ML, Guerrier, M, Strous, G, Wälchli, S, Espanel, X

Mol Endocrinol 2003
Participants
Participates
Catalyst Activity

protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane]

Orthologous Events
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