CTSD(65-412) [lysosomal lumen]

Stable Identifier
R-HSA-1181223
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Cathepsin D, Cathepsin D component recommendedName: Cathepsin D light chain /component component recommendedName: Cathepsin D heavy chain /component, CTSD, CATD_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P07339 CTSD
Gene Names
CTSD, CPSD
Chain
signal peptide:1-20, propeptide:21-64, chain:65-412, chain:65-162, chain:169-412
Reference Genes
BioGPS Gene:1509 CTSD
COSMIC (genes):CTSD CTSD
CTD Gene:1509 CTSD
dbSNP Gene:1509 CTSD
ENSEMBL:ENSG00000117984 CTSD
HGNC:2529 CTSD
KEGG:hsa:1509 CTSD
Monarch:1509 CTSD
NCBI Gene:1509 CTSD
OMIM:116840 CTSD
UCSC:P07339 CTSD
Reference Transcript
Other Identifiers
11755925_s_at
11757307_s_at
11757848_s_at
1509
16734313
16734330
200766_3p_at
200766_PM_at
200766_at
239_at
3358964
3358965
3358966
3358967
3358968
3358969
3358970
3358971
3358972
3358973
3358974
3358975
3358976
3358977
3358979
3358980
3358981
3358982
3358983
3358984
3358986
7945666
A_23_P52556
A_33_P3243907
GE61336
GO:0000045
GO:0002376
GO:0003824
GO:0004175
GO:0004190
GO:0004197
GO:0005515
GO:0005576
GO:0005615
GO:0005764
GO:0005765
GO:0005773
GO:0006508
GO:0008233
GO:0010008
GO:0016787
GO:0019886
GO:0030163
GO:0030312
GO:0031012
GO:0031410
GO:0031904
GO:0035580
GO:0038020
GO:0042159
GO:0042470
GO:0043065
GO:0043202
GO:0043226
GO:0043280
GO:0045121
GO:0062023
GO:0070001
GO:0070062
GO:0070201
GO:0140096
GO:1901143
GO:1904724
GO:1904813
HMNXSV003011659
ILMN_1674038
M63138_at
PH_hs_0016632
TC11001267.hg
TC11003472.hg
g4503142_3p_at
g4503142_3p_x_at
Participates
as a candidate of
as a member of
Other forms of this molecule
CTSD(65-412) [extracellular region]
CTSD(65-412) [plasma membrane]
CTSD(169-412) [endosome lumen]
CTSD(65-161) [endosome lumen]
CTSD(65-412) [specific granule lumen]
CTSD(65-412) [tertiary granule lumen]
CTSD(65-412) [ficolin-1-rich granule lumen]
CTSD(169-412) [extracellular region]
CTSD(65-161) [extracellular region]
CTSD(169-412) [lysosomal lumen]
CTSD(65-161) [lysosomal lumen]
Inferred To
CTSD [lysosomal lumen] (Bos taurus)
CTSD [lysosomal lumen] (Canis familiaris)
CTSD [lysosomal lumen] (Gallus gallus)
CTSD [lysosomal lumen] (Sus scrofa)
PMII [lysosomal lumen] (Plasmodium falciparum)
Ctsd [lysosomal lumen] (Mus musculus)
Ctsd [lysosomal lumen] (Rattus norvegicus)
PMIII [lysosomal lumen] (Plasmodium falciparum)
PMX [lysosomal lumen] (Plasmodium falciparum)
ctsd [lysosomal lumen] (Danio rerio)
ctsd [lysosomal lumen] (Xenopus tropicalis)
ctsD [lysosomal lumen] (Dictyostelium discoideum)
Dmel\CG5860 [lysosomal lumen] (Drosophila melanogaster)
PMV [lysosomal lumen] (Plasmodium falciparum)
PMIX [lysosomal lumen] (Plasmodium falciparum)
Homologues of CTSD(65-412) [lysosomal lumen] (Plasmodium falciparum)
PMI [lysosomal lumen] (Plasmodium falciparum)
CTSD(65-412) [lysosomal lumen] (Plasmodium falciparum)
PMIV [lysosomal lumen] (Plasmodium falciparum)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Investigational
IntEnz
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O00308 WWP2  1 0.556 3
 UniProt:Q8NBJ7 SUMF2  1 0.556 3
 UniProt:P13569 CFTR  17 0.483 7
 UniProt:P04578 env  7 0.462 2
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