Me3K5-H3F3A [nucleoplasm]

Stable Identifier
R-HSA-1214216
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Histone H3.3 with trimethylated lysine-4, H3F3A, H33_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P84243 H3-3A
Gene Names
H3-3A, H3.3A, H3F3, H3F3A, PP781, H3-3B, H3.3B, H3F3B
Chain
initiator methionine:, chain:2-136
Reference Genes
BioGPS Gene:3020 H3-3A
BioGPS Gene:3021 H3-3A
COSMIC (genes):H3F3A H3-3A
COSMIC (genes):H3F3B H3-3A
CTD Gene:3020 H3-3A
CTD Gene:3021 H3-3A
dbSNP Gene:3020 H3-3A
dbSNP Gene:3021 H3-3A
ENSEMBL:ENSG00000132475 H3F3B
ENSEMBL:ENSG00000163041 H3F3A
HGNC:4764 H3-3A
HGNC:4765 H3-3A
KEGG:hsa:3020 H3-3A
KEGG:hsa:3021 H3-3A
Monarch:3020 H3-3A
Monarch:3021 H3-3A
NCBI Gene:3020 H3-3A
NCBI Gene:3021 H3-3A
OMIM:601058 H3-3A
OMIM:601128 H3-3A
UCSC:P84243 H3-3A
Reference Transcript
Other Identifiers
11715189_s_at
11739481_x_at
11754775_s_at
11756379_x_at
11757037_s_at
11757038_x_at
11758593_s_at
11760281_at
16650285
16650289
16650291
16650293
16650295
16650297
16650299
16650301
16650303
16650305
16650307
16650309
16650311
16678128
16848888
16848894
16887898
18670604
18670605
18670606
18670607
18670608
200080_PM_s_at
200080_s_at
208755_PM_x_at
208755_x_at
209069_PM_s_at
209069_s_at
211940_PM_x_at
211940_x_at
211997_PM_x_at
211997_x_at
211998_PM_at
211998_at
211999_PM_at
211999_at
213828_PM_x_at
213828_x_at
2383063
2383064
2383065
2383067
2383068
2383069
2383070
2383071
2383072
2383073
2383075
2383076
2383077
2383078
2383079
2383080
2516451
2516452
2516453
2516454
2516455
254_at
2739999
2740001
2740002
2786723
2786725
2786727
2786729
3020
3021
31510_s_at
3449959
3493224
3493226
3493227
3770943
3770945
3770946
3770947
3770948
3770949
3770950
3770951
3770952
3770953
3770954
3770955
3770956
3770957
3770958
3770959
3770960
3770961
3770963
3770964
3989613
3989617
3989619
3989621
4003653
73099_at
7894282
7895579
7896511
7910124
8018439
8046515
8102860
8169740
90048_at
A_14_P138929
A_23_P152516
A_23_P23141
A_24_P105298
A_24_P82419
A_24_P91035
A_32_P208424
A_33_P3410194
GE80224
GE80274
GO:0000228
GO:0000775
GO:0000781
GO:0000785
GO:0000786
GO:0000939
GO:0000978
GO:0000979
GO:0001556
GO:0001649
GO:0001740
GO:0003677
GO:0005198
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006334
GO:0006997
GO:0007283
GO:0007286
GO:0007338
GO:0007566
GO:0008283
GO:0008584
GO:0022414
GO:0030154
GO:0030307
GO:0030527
GO:0031492
GO:0031508
GO:0031509
GO:0032200
GO:0032991
GO:0035264
GO:0042692
GO:0043226
GO:0043229
GO:0046982
GO:0048477
GO:0048856
GO:0065003
GO:0070062
GO:0090230
GO:1902340
HMNXSV003016235
HMNXSV003029246
HMNXSV003033897
HMNXSV003045451
Hs.180877.1.A1_3p_s_at
Hs.180877.1.A3_3p_at
Hs.180877.1.A4_3p_at
Hs.181307.4.A1_3p_a_at
ILMN_1656082
ILMN_1695706
ILMN_1699015
ILMN_2106331
ILMN_2402930
ILMN_2402936
M11353_at
PH_hs_0027287
PH_hs_0032025
PH_hs_0040066
TC01001857.hg
TC01005067.hg
TC17001882.hg
TC17001883.hg
TC17002787.hg
X05855_s_at
Z48950_at
g12654576_3p_s_at
Participates
as a member of
as a candidate of
Other forms of this molecule
H3F3A [nucleoplasm]
Me2K5-H3F3A [nucleoplasm]
Me3K-28-H3F3A [nucleoplasm]
Me3K-10-H3F3A [nucleoplasm]
p-T12,Me3K-10-H3F3A [nucleoplasm]
p-T12, Me2K-10-H3F3A [nucleoplasm]
p-T12,MeK-H3F3A [nucleoplasm]
p-T12-H3F3A [nucleoplasm]
Me2K-10-H3F3A [nucleoplasm]
H3F3A [extracellular region]
AcK10-H3F3A [nucleoplasm]
Me2K5,Me2aR2-H3F3A [nucleoplasm]
H3R17me2a [nucleoplasm]
MeK28-H3-3A [nucleoplasm]
Me1K5-H3-3A [nucleoplasm]
2xAcK-H3F3A [nucleoplasm]
MeK-H3F3A [nucleoplasm]
Inferred To
hht1 [nucleoplasm] (Schizosaccharomyces pombe)
h3f3b.1 [nucleoplasm] (Danio rerio)
HHT2 [nucleoplasm] (Saccharomyces cerevisiae)
H3-X [nucleoplasm] (Gallus gallus)
His3.3A [nucleoplasm] (Drosophila melanogaster)
Me3K5-H3F3A [nucleoplasm] (Bos taurus)
H3-3A [nucleoplasm] (Sus scrofa)
His3.3B [nucleoplasm] (Drosophila melanogaster)
Me3K5-H3f3a [nucleoplasm] (Mus musculus)
hht3 [nucleoplasm] (Schizosaccharomyces pombe)
his-71 [nucleoplasm] (Caenorhabditis elegans)
Homologues of Me3K5-H3F3A [nucleoplasm] (Drosophila melanogaster)
Homologues of Me3K5-H3F3A [nucleoplasm] (Schizosaccharomyces pombe)
H3-3b [nucleoplasm] (Rattus norvegicus)
LOC612779 [nucleoplasm] (Canis familiaris)
Modified Residues
Name
N6,N6,N6-trimethyl-L-lysine at 5
Coordinate
5
PsiMod Name
N6,N6,N6-trimethyl-L-lysine [MOD:00083]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.
Cross References
RefSeq
OpenTargets
ENSEMBL
HPA
PRO
Pharos - Targets
GlyGen
PDB
Interactors (26)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62805 H4C1  17 0.861 12
 UniProt:Q9UER7 DAXX  13 0.85 8
 UniProt:Q9UER7-1 DAXX      0.781 21
 UniProt:Q9NVP2 ASF1B      0.723 5
 UniProt:Q8R5C8 ZMY11      0.691 6
 UniProt:P45973 CBX5  2 0.667 3
 UniProt:P49736 MCM2  1 0.656 3
 UniProt:Q09028 RBBP4  1 0.643 3
 UniProt:P54198 HIRA  1 0.643 3
 UniProt:Q13111 CAF1A      0.623 3
 UniProt:Q9Y6K1 DNMT3A  2 0.618 7
 UniProt:Q15910 EZH2  1 0.597 7
 UniProt:Q9Y294 ASF1A  1 0.597 5
 UniProt:Q8IZL8 PELP1  1 0.591 11
 UniProt:P46100 ATRX  20 0.564 2
 UniProt:P49321-2 NASP      0.556 3
 UniProt:Q96KQ7 EHMT2  1 0.547 2
 UniProt:Q5VWG9 TAF3  1 0.544 3
 UniProt:Q13112 CAF1B      0.527 2
 UniProt:Q8IV20 LACC1      0.527 2
 UniProt:Q16576 RBBP7  1 0.527 2
 UniProt:P10636-8 MAPT  3 0.527 5
 UniProt:Q9Y496 KIF3A  3 0.527 2
 UniProt:Q8WVS4 DYNC2I1  2 0.508 2
 UniProt:Q96EX3 DYNC2I2  2 0.508 2
 UniProt:C4QZQ7 C4QZQ7      0.495 2
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