Peroxynitrite oxidizes Peptide-Methionine residues

Stable Identifier
R-HSA-1222411
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
ReviewStatus
5/5
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Within the bacterial cell, peroxynitrite (ONOO-) is able to oxidize methionine residues on peptides, forming methionine sulfoxide residues with itself being reduced to nitrite (NOO-) (Pryor et al. 1994).
Literature References
PubMed ID Title Journal Year
7972029 One- and two-electron oxidations of methionine by peroxynitrite

Jin, X, Squadrito, GL, Pryor, WA

Proc Natl Acad Sci U S A 1994
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