Reactome | FOXH1 [nucleoplasm]

FOXH1 [nucleoplasm]

Stable Identifier

R-HSA-1225914

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Forkhead box protein H1, FOXH1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9BYR8 KRTAP3-1

Expand all

External Reference Information

External Reference

UniProt:O75593 FOXH1

Gene Names

FOXH1, FAST1, FAST2

Chain

chain:1-365

Reference Genes

BioGPS Gene:8928 FOXH1

COSMIC (genes):FOXH1 FOXH1

CTD Gene:8928 FOXH1

dbSNP Gene:8928 FOXH1

ENSEMBL:ENSG00000160973 FOXH1

HGNC:3814 FOXH1

Monarch:8928 FOXH1

NCBI Gene:8928 FOXH1

OMIM:603621 FOXH1

UCSC:O75593 FOXH1

Reference Transcript

RefSeq:NM_003923.2 FOXH1

Other Identifiers

11732008_a_at

17082752

207644_PM_at

207644_at

231407_PM_s_at

231407_s_at

3158742

3158743

3158744

3158745

3158746

3158747

3158748

3158749

3158750

3158751

3158752

31912_at

3231251

50227_s_at

8153828

8928

GE79568

GO:0000122

GO:0000785

GO:0000976

GO:0000981

GO:0000987

GO:0001228

GO:0001947

GO:0003139

GO:0003140

GO:0003151

GO:0003215

GO:0003222

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005667

GO:0006355

GO:0006357

GO:0007179

GO:0007368

GO:0009952

GO:0010556

GO:0019904

GO:0030154

GO:0032444

GO:0033147

GO:0035054

GO:0035909

GO:0038092

GO:0043226

GO:0043425

GO:0043433

GO:0043565

GO:0045893

GO:0045944

GO:0046332

GO:0048318

GO:0048856

GO:0050681

GO:0060766

GO:0070365

GO:0070410

GO:0070412

GO:0071345

GO:0080090

GO:0140110

GO:0140297

HMNXSV003009175

Hs.92679.0.A1_3p_at

ILMN_1798808

PH_hs_0009678

TC08001753.hg

g4503656_3p_at

g4503656_3p_x_at

Participates

as a component of

as an input of

Cross References

OpenTargets

ENSG00000160973

ENSEMBL

ENSP00000366534, ENST00000377317

HPA

ENSG00000160973-FOXH1

PRO

O75593

Pharos - Targets

O75593

Orphanet

FOXH1

HMDB Protein

HMDBP14544

PDB

5XOC, 7YZB

Interactors (59)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P84022 SMAD3	20	p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-177104) p-S423,S425-SMAD3 [cytosol] (R-HSA-171184) SMAD3 [cytosol] (R-HSA-170855) p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-2176471) Ub,p-T179,S423,S425-SMAD3 [nucleoplasm] (R-HSA-9773841) 2xADPRib-p-S423,S425-SMAD3 [nucleoplasm] (R-HSA-2187326) SMAD3 [nucleoplasm] (R-HSA-206150) p-S208-SMAD3 [cytosol] (R-HSA-9731114) SMAD3 S425C [cytosol] (R-HSA-3308499) SMAD3 Y298* [cytosol] (R-HSA-9668769) SMAD3 R368* [cytosol] (R-HSA-9668768) SMAD3 E383* [cytosol] (R-HSA-9668775) SMAD3 S425F [cytosol] (R-HSA-8944158) SMAD3 Q322* [cytosol] (R-HSA-9668773) SMAD3 Q358* [cytosol] (R-HSA-9668772) SMAD3 E246* [cytosol] (R-HSA-9668776) SMAD3 W326* [cytosol] (R-HSA-9668766) SMAD3 Y384* [cytosol] (R-HSA-9668782) SMAD3 Q316* [cytosol] (R-HSA-9668765) p-S423,S425-SMAD3 R268H [cytosol] (R-HSA-3315080)	0.675	4
UniProt:Q15796 SMAD2	20	Ub-SMAD2 [cytosol] (R-HSA-6782774) p-S465,S467-SMAD2 P305L [cytosol] (R-HSA-3315471) p-S465,S467-SMAD2 D300A [cytosol] (R-HSA-3315064) p-S465,S467-SMAD2 D300N [cytosol] (R-HSA-3315066) p-S465,S467-SMAD2 A354T [cytosol] (R-HSA-3315474) p-S465,S467-SMAD2 P305Q [cytosol] (R-HSA-3315070) p-S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009185) p-S465,S467-SMAD2 [cytosol] (R-HSA-3009186) SMAD2 [cytosol] (R-HSA-3006353) p-T220,S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009189) Ub,p-T220,S465,S467-SMAD2 [nucleoplasm] (R-HSA-9773843) SMAD2 [nucleoplasm] (R-HSA-3006352) p-S250-SMAD2 [cytosol] (R-HSA-9731121) SMAD2 Q429* [cytosol] (R-HSA-9668727) SMAD2 S467P [cytosol] (R-HSA-3304375) SMAD2 L315* [cytosol] (R-HSA-9668725) SMAD2 E439* [cytosol] (R-HSA-9668724) SMAD2 Q455* [cytosol] (R-HSA-9668731) SMAD2 S306* [cytosol] (R-HSA-9668730) SMAD2 S296* [cytosol] (R-HSA-9668729)	0.675	4
UniProt:Q03989 ARI5A			0.601	4
UniProt:P40199 CEACAM6	2	GPI-CEACAM6 [plasma membrane] (R-HSA-204085) GPI-CEACAM6 [azurophil granule membrane] (R-HSA-6799133)	0.556	3
UniProt:P0C7T5 ATX1L			0.556	6
UniProt:Q6ZRY4 RBPS2			0.556	3
UniProt:Q5SWW7 CJ055			0.556	3
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.556	3
UniProt:Q96F45 ZN503			0.556	3
UniProt:Q8N1L9 BATF2			0.556	3
UniProt:Q9BYR6 KRTAP3-3	1	KRTAP3-3 [cytosol] (R-HSA-6809859)	0.556	3
IntAct:EBI-22616457 CCSB ORF ID			0.556	5
UniProt:Q15038 DAZP2			0.556	5
UniProt:Q3LI70 KRTAP19-6	1	KRTAP19-6 [cytosol] (R-HSA-6810286)	0.556	3
UniProt:Q86UY5 FAM83A	1	FAM83A [cytosol] (R-HSA-9851391)	0.556	3
UniProt:Q9BYR8 KRTAP3-1	1	KRTAP3-1 [cytosol] (R-HSA-6809868)	0.556	3
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q9Y5J3 HEY1	1	HEY1 [nucleoplasm] (R-HSA-1606744)	0.556	3
UniProt:Q8TDS5 OXER1	1	OXER1 [plasma membrane] (R-HSA-416425)	0.556	3
UniProt:A8MTQ0 NOTO	1	NOTO [nucleoplasm] (R-HSA-9796216)	0.556	3
UniProt:Q6NVU6 UFSP1			0.556	3
UniProt:Q14774 HLX			0.556	3
UniProt:Q9ULV5-2 HSF4			0.556	3
UniProt:Q86WV8 Q86WV8			0.556	5
UniProt:P05813 CRBA1			0.556	3
UniProt:Q9Y6H3 ATP23			0.556	3
UniProt:P19801 AOC1	3	AOC1 [specific granule lumen] (R-HSA-6806138) AOC1 [extracellular region] (R-HSA-6806164) AOC1 [plasma membrane] (R-HSA-2889048)	0.556	3
UniProt:A1KXE4-2 FAM168B			0.556	3
UniProt:Q3SY46 KRTAP13-3	1	KRTAP13-3 [cytosol] (R-HSA-6810267)	0.556	3
IntAct:EBI-22320186 CCSB ORF ID			0.556	3
IntAct:EBI-23202138 CCSB ORF ID			0.556	3
UniProt:Q9BSH5 HDHD3			0.556	3
UniProt:O43711 TLX3			0.556	3
UniProt:Q96K80 ZC3HA			0.556	3
UniProt:Q5BKX5-3 ACTMAP			0.556	3
UniProt:Q96PV4 PNMA5			0.556	3
UniProt:P35548 MSX2	1	MSX2 [nucleoplasm] (R-HSA-9007760)	0.556	3
UniProt:Q14847-2 LASP1			0.556	3
UniProt:Q8IUC1 KRTAP11-1	1	KRTAP11-1 [cytosol] (R-HSA-6810294)	0.556	3
UniProt:Q8IUC3 KRA71			0.556	3
UniProt:O43186 CRX			0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:Q92734 TFG	7	TFG [cytosol] (R-HSA-5688159) TFG(1-240)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699806) TFG(1-138)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699874) TFG(1-193)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699887) TFG(1-193)-p-7Y-ALK(1058-1620) [cytosol] (R-HSA-9702029) TFG(1-240)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9702038) TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9702019)	0.556	3
UniProt:Q5T6F2 UBAP2			0.556	3
UniProt:O95416 SOX14			0.556	3
UniProt:Q9H5F2 CFA68			0.556	3
UniProt:Q9UGK8 SRGEF			0.556	3
UniProt:O15496 PLA2G10	1	PLA2G10 [extracellular region] (R-HSA-1498793)	0.556	3
UniProt:O75864 PPR37			0.556	3
IntAct:EBI-22412087 CCSB ORF ID			0.556	3
UniProt:P86480 PR20D			0.556	3
UniProt:Q3LHN2 KRTAP19-2	1	KRTAP19-2 [cytosol] (R-HSA-6810262)	0.556	3
UniProt:O60548 FOXD2			0.556	3
UniProt:Q96M29 TEKT5			0.556	3
UniProt:Q8TBY0 RBM46			0.556	3
UniProt:Q53HC5 KLH26			0.556	3
UniProt:Q3SYF9 KRTAP19-7	1	KRTAP19-7 [cytosol] (R-HSA-6810305)	0.556	3
UniProt:P10275 AR	4	AR [cytosol] (R-HSA-5618082) AR [nucleoplasm] (R-HSA-446174) monoSUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984)	0.508	3

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