Reactome | EGLN3 [nucleoplasm]

EGLN3 [nucleoplasm]

Stable Identifier

R-HSA-1234104

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Egl nine homolog 3, EGLN3_HUMAN, PHD3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H6Z9 EGLN3

Gene Names

EGLN3

Chain

chain:1-239

Reference Genes

BioGPS Gene:112399 EGLN3

COSMIC (genes):EGLN3 EGLN3

CTD Gene:112399 EGLN3

dbSNP Gene:112399 EGLN3

ENSEMBL:ENSG00000129521 EGLN3

HGNC:14661 EGLN3

KEGG:hsa:112399 EGLN3

Monarch:112399 EGLN3

NCBI Gene:112399 EGLN3

OMIM:606426 EGLN3

UCSC:Q9H6Z9 EGLN3

Reference Transcript

Other Identifiers

112399

11733852_at

11757444_a_at

11760606_s_at

219232_PM_s_at

219232_s_at

222847_PM_s_at

222847_s_at

3560413

3560414

3560415

3560416

3560417

3560418

3560419

3560421

3560422

3560423

3560432

3560433

3560434

3560435

3560436

3560437

3560438

3560439

3560440

3560441

3560442

3560443

3560444

3560445

3560454

3560467

3560468

3560469

3560470

3560471

3560477

3560478

3560479

3560480

3560481

3560491

3560492

3560546

60511_at

62869_at

7978544

81319_at

A_21_P0008419

A_23_P360379

A_33_P3256952

GE56932

GE755463

GE85161

GO:0001666

GO:0003824

GO:0005506

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006915

GO:0006919

GO:0006974

GO:0008198

GO:0012501

GO:0016491

GO:0016705

GO:0016706

GO:0018126

GO:0031418

GO:0031545

GO:0042127

GO:0043226

GO:0043523

GO:0046872

GO:0051213

GO:0071456

GO:0140096

GO:0160082

HMNXSV003011883

HMNXSV003025676

HMNXSV003035924

Hs.18878.0.A1_3p_a_at

ILMN_1667626

ILMN_1693838

PH_hs_0025932

TC14001022.hg

TC14001965.hg

g11545786_3p_a_at

p19290

p19291

Participates

as a component of

EGLN3:AscH-:Fe2+ [nucleoplasm] (Homo sapiens)

Other forms of this molecule

EGLN3 [cytosol]

Inferred To

Hph [nucleoplasm] (Drosophila melanogaster)

EGLN3 [nucleoplasm] (Bos taurus)

EGLN3 [nucleoplasm] (Caenorhabditis elegans)

EGLN3 [nucleoplasm] (Canis familiaris)

EGLN3 [nucleoplasm] (Gallus gallus)

EGLN3 [nucleoplasm] (Mus musculus)

EGLN3 [nucleoplasm] (Rattus norvegicus)

EGLN3 [nucleoplasm] (Sus scrofa)

egln3 [nucleoplasm] (Xenopus tropicalis)

Cross References

Guide to Pharmacology - Targets

2834

ENSEMBL

ENSP00000250457, ENST00000250457

OpenTargets

ENSG00000129521

HPA

ENSG00000129521-EGLN3

ZINC - Substances

EGLN3_HUMAN

ZINC target

Q9H6Z9

PRO

Q9H6Z9

Pharos - Targets

Q9H6Z9

ZINC - Predictions - Purchasable

EGLN3_HUMAN

HMDB Protein

HMDBP09212

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16665 HIF1A	7	HIF1A [nucleoplasm] (R-HSA-1234135) HIF1A [cytosol] (R-HSA-1234102) p-Y565-HIF1A [cytosol] (R-HSA-8857584) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) 2xHP-HIF1A [cytosol] (R-HSA-1234131) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105) HN-HIF1A [cytosol] (R-HSA-1234110)	0.881	7
UniProt:Q16659 MAPK6 gene	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.681	6
UniProt:Q13123 IK	1	IK [nucleoplasm] (R-HSA-9770239)	0.556	3
UniProt:Q13085 ACACA	2	ACACA [cytosol] (R-HSA-1660609) Btn-ACACA [cytosol] (R-HSA-2976730)	0.527	2
UniProt:P14618-1 PKM	2	PKM-1 [cytosol] (R-HSA-71667) PolyUb-PKM-1 [cytosol] (R-HSA-9861692)	0.524	2

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