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UBE2D1,2,3 [cytosol]
Stable Identifier
R-HSA-1234120
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Synonyms
UbcH5a,b,c
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to hypoxia (Homo sapiens)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Homo sapiens)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TICAM1, RIP1-mediated IKK complex recruitment (Homo sapiens)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Homo sapiens)
RIP1 ubiqutin ligases [cytosol] (Homo sapiens)
c-IAP1:UBE2D [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
c-IAP2:UBE2D [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
IKK complex recruitment mediated by RIP1 (Homo sapiens)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Homo sapiens)
RIP1 ubiqutin ligases [cytosol] (Homo sapiens)
c-IAP1:UBE2D [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
c-IAP2:UBE2D [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
Regulation of necroptotic cell death (Homo sapiens)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
PELI1 ubiquitinates RIPK3 at K363 (Homo sapiens)
UbcH5a,b,c E2 Conjugating Enzyme:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
TNF signaling (Homo sapiens)
TNFR1-induced NF-kappa-B signaling pathway (Homo sapiens)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3 [cytosol] (Homo sapiens)
Participants
members
UBE2D1 [cytosol]
(Homo sapiens)
UBE2D2 [cytosol]
(Homo sapiens)
UBE2D3 [cytosol]
(Homo sapiens)
Participates
as an output of
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Homo sapiens)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)
Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha (Homo sapiens)
as a component of
UbcH5a,b,c E2 Conjugating Enzyme:Ubiquitin [cytosol] (Homo sapiens)
UBE2D1,2,3:Ubiquitin [cytosol] (Homo sapiens)
Inferred To
UBE2D1 [cytosol]
(Plasmodium falciparum)
ube2d3 [cytosol]
(Xenopus tropicalis)
Homologues of UBE2D1 [cytosol]
(Dictyostelium discoideum)
Homologues of UBE2D1 [cytosol]
(Saccharomyces cerevisiae)
Homologues of UBE2D1 [cytosol]
(Schizosaccharomyces pombe)
eff [cytosol]
(Drosophila melanogaster)
UBE2D1,2,3 [cytosol]
(Bos taurus)
UBE2D1,2,3 [cytosol]
(Canis familiaris)
UBE2D1,2,3 [cytosol]
(Danio rerio)
UBE2D1,2,3 [cytosol]
(Gallus gallus)
UBE2D1,2,3 [cytosol]
(Mus musculus)
UBE2D1,2,3 [cytosol]
(Rattus norvegicus)
UBE2D1,2,3 [cytosol]
(Sus scrofa)
let-70 [cytosol]
(Caenorhabditis elegans)
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