Partial proteolysis of antigen in phagolysosomes

Stable Identifier
R-HSA-1236938
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
phagolysosome
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Partial proteolysis of antigen in phagolysosomes
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Phagocytosed particulate antigens are partially digested in the lumen of phagolysosomes by various lysosomal hydrolases.

Literature References
PubMed ID Title Journal Year
19265109 Autophagy and its role in MHC-mediated antigen presentation

Blum, JS, Crotzer, VL

J Immunol 2009
Participants
Input
Output
Participates
as an event of
Catalyst Activity

hydrolase activity of Unknown hydrolase [phagolysosome]

Physical Entity
Unknown hydrolase [phagolysosome] (Homo sapiens)
Activity
hydrolase activity (GO:0016787)
Authored
Garapati, P V  (2011-03-28)
Reviewed
English, L  (2011-05-13)
Desjardins, M  (2011-05-13)
Created
Garapati, P V  (2011-03-28)
Cite Us!