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NRG1/2:ERBB3 [plasma membrane]
Stable Identifier
R-HSA-1247495
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Signaling by ERBB2 KD Mutants (Homo sapiens)
ERBB2 KD mutants heterodimerize (Homo sapiens)
Heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Ligand-Activated (EGFR,ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)
Heterodimers of ERBB2 KD mutants [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 KD mutants:Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD heterodimers trans-autophosphorylate (Homo sapiens)
ERBB2 TMD/JMD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants hetrodimerize (Homo sapiens)
ERBB2 TMD/JMD mutants:Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB2 (Homo sapiens)
ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR/ERBB3/ERBB4 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
ERBB3 binds neuregulins (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
SRC family kinases phosphorylate ERBB2 (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
ERBB2 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)
p-Y877-ERBB2 heterodimers [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
ERBB4 forms heterodimers with ERBB3 (Homo sapiens)
ERBB4:ERBB3 heterodimer [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3 [plasma membrane] (Homo sapiens)
Participants
components
ERBB3-1 [plasma membrane]
(Homo sapiens)
NRG1/2 [extracellular region]
(Homo sapiens)
Participates
as a candidate of
Ligand-Activated EGFR,(ERBB3,ERBB4) [plasma membrane] (Homo sapiens)
as a member of
Ligand-Activated ERBB3,(EGFR,ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR,ERBB3,(ERBB4) [plasma membrane] (Homo sapiens)
Ligand-Activated EGFR/ERBB3/ERBB4 [plasma membrane] (Homo sapiens)
as a component of
ERBB4:ERBB3 heterodimer [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Homo sapiens)
NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane] (Homo sapiens)
as an input of
ERBB4 forms heterodimers with ERBB3 (Homo sapiens)
as an output of
ERBB3 binds neuregulins (Homo sapiens)
Inferred To
NRG1/2:ERBB3 [plasma membrane]
(Bos taurus)
NRG1/2:ERBB3 [plasma membrane]
(Canis familiaris)
NRG1/2:ERBB3 [plasma membrane]
(Danio rerio)
NRG1/2:ERBB3 [plasma membrane]
(Drosophila melanogaster)
NRG1/2:ERBB3 [plasma membrane]
(Gallus gallus)
NRG1/2:ERBB3 [plasma membrane]
(Mus musculus)
NRG1/2:ERBB3 [plasma membrane]
(Rattus norvegicus)
NRG1/2:ERBB3 [plasma membrane]
(Sus scrofa)
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