OPLAH hydrolyses OPRO to L-Glu

Stable Identifier
R-HSA-1247935
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Cleavage of 5-oxoproline to form glutamate
ReviewStatus
5/5
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5-oxoprolinase catalyzes the cleavage of 5-oxoproline to form L-glutamate, coupled to the hydrolysis of ATP to ADP and inorganic phosphate (Chen et al, 1998).
Literature References
PubMed ID Title Journal Year
9516961 Characterization of 5-oxo-L-prolinase in normal and tumor tissues of humans and rats: a potential new target for biochemical modulation of glutathione

Schecter, RL, Chen, X, Batist, G, Hayward, MA, Alpert, LC, Griffith, OW

Clin Cancer Res 1998
Participants
Participates
Catalyst Activity

5-oxoprolinase (ATP-hydrolyzing) activity of OPLAH [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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