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Homodimerization of ERBB4
Stable Identifier
R-HSA-1250220
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
,
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ERBB4 (Homo sapiens)
Homodimerization of ERBB4 (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Ligand stimulated ERBB4 forms homodimers (Sweeney et al. 2000).
Literature References
PubMed ID
Title
Journal
Year
10867024
Ligand discrimination in signaling through an ErbB4 receptor homodimer
Carraway KL, 3rd
,
Riese DJ, 2nd
,
Cantley, LC
,
Diamonti, AJ
,
Lai, C
,
Sweeney, C
J Biol Chem
2000
Participants
Input
x 2
NRGs/EGF-like ligands:ERBB4 [plasma membrane]
(Homo sapiens)
Output
ERBB4 homodimers [plasma membrane]
(Homo sapiens)
Participates
as an event of
Signaling by ERBB4 (Homo sapiens)
Orthologous Events
Homodimerization of ERBB4 (Bos taurus)
Homodimerization of ERBB4 (Canis familiaris)
Homodimerization of ERBB4 (Danio rerio)
Homodimerization of ERBB4 (Drosophila melanogaster)
Homodimerization of ERBB4 (Gallus gallus)
Homodimerization of ERBB4 (Mus musculus)
Homodimerization of ERBB4 (Rattus norvegicus)
Homodimerization of ERBB4 (Sus scrofa)
Homodimerization of ERBB4 (Xenopus tropicalis)
Authored
Orlic-Milacic, M (2011-11-04)
Stern, DF (2019-02-21)
Reviewed
Zeng, F (2011-11-11)
Harris, RC (2011-11-11)
Earp HS, 3rd (2012-02-20)
Misior, AM (2012-02-20)
Created
Orlic-Milacic, M (2011-04-15)
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